Novel aromatics bearing 4-O-methylglucose unit isolated from the oriental crude drug Bombyx Batryticatus

Haruhisa Kikuchi; Nahoko Takahashi; Yoshiteru Oshima

doi:10.1016/j.tetlet.2003.10.159

Novel aromatics bearing 4-O-methylglucose unit isolated from the oriental crude drug Bombyx Batryticatus

Haruhisa Kikuchi, Nahoko Takahashi, Yoshiteru Oshima

Research output: Contribution to journal › Article › peer-review

28 Citations (Scopus)

Abstract

Oriental crude drug, Bombyx Batryticatus, is dried silkworm larva, Bombyx mori L., which are dead and stiffened due to a Beauveria bassiana infection. In traditional Japanese, Korean, and Chinese medicine, it is employed as analgesic and anticonvulsant. We investigated the constituents of Bombyx Batryticatus and isolated four novel aromatics bearing 4-O-methylglucose moiety, BB-1, 2, 3, and 4 (1-4). It is speculated that these compounds are produced by an interaction between plants, insects, and microorganisms.

Original language	English
Pages (from-to)	367-370
Number of pages	4
Journal	Tetrahedron Letters
Volume	45
Issue number	2
DOIs	https://doi.org/10.1016/j.tetlet.2003.10.159
Publication status	Published - 2004 Jan 5
Externally published	Yes

Keywords

Beauveria bassiana
Biological interaction
Bombyx Batryticatus
Microbial biotransformation
Silkworm

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/j.tetlet.2003.10.159

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title = "Novel aromatics bearing 4-O-methylglucose unit isolated from the oriental crude drug Bombyx Batryticatus",

abstract = "Oriental crude drug, Bombyx Batryticatus, is dried silkworm larva, Bombyx mori L., which are dead and stiffened due to a Beauveria bassiana infection. In traditional Japanese, Korean, and Chinese medicine, it is employed as analgesic and anticonvulsant. We investigated the constituents of Bombyx Batryticatus and isolated four novel aromatics bearing 4-O-methylglucose moiety, BB-1, 2, 3, and 4 (1-4). It is speculated that these compounds are produced by an interaction between plants, insects, and microorganisms.",

keywords = "Beauveria bassiana, Biological interaction, Bombyx Batryticatus, Microbial biotransformation, Silkworm",

author = "Haruhisa Kikuchi and Nahoko Takahashi and Yoshiteru Oshima",

note = "Funding Information: This work was supported in part by Grant-in-Aid for Scientific Research (No. 13024208) from the Ministry of Education, Science, Sports and Culture of Japan, Shorai Foundation for Science and Technology, Hokuto Foundation for Biological Science, and Takeda Science Foundation.",

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doi = "10.1016/j.tetlet.2003.10.159",

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pages = "367--370",

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T1 - Novel aromatics bearing 4-O-methylglucose unit isolated from the oriental crude drug Bombyx Batryticatus

AU - Kikuchi, Haruhisa

AU - Takahashi, Nahoko

AU - Oshima, Yoshiteru

N1 - Funding Information: This work was supported in part by Grant-in-Aid for Scientific Research (No. 13024208) from the Ministry of Education, Science, Sports and Culture of Japan, Shorai Foundation for Science and Technology, Hokuto Foundation for Biological Science, and Takeda Science Foundation.

PY - 2004/1/5

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N2 - Oriental crude drug, Bombyx Batryticatus, is dried silkworm larva, Bombyx mori L., which are dead and stiffened due to a Beauveria bassiana infection. In traditional Japanese, Korean, and Chinese medicine, it is employed as analgesic and anticonvulsant. We investigated the constituents of Bombyx Batryticatus and isolated four novel aromatics bearing 4-O-methylglucose moiety, BB-1, 2, 3, and 4 (1-4). It is speculated that these compounds are produced by an interaction between plants, insects, and microorganisms.

AB - Oriental crude drug, Bombyx Batryticatus, is dried silkworm larva, Bombyx mori L., which are dead and stiffened due to a Beauveria bassiana infection. In traditional Japanese, Korean, and Chinese medicine, it is employed as analgesic and anticonvulsant. We investigated the constituents of Bombyx Batryticatus and isolated four novel aromatics bearing 4-O-methylglucose moiety, BB-1, 2, 3, and 4 (1-4). It is speculated that these compounds are produced by an interaction between plants, insects, and microorganisms.

KW - Beauveria bassiana

KW - Biological interaction

KW - Bombyx Batryticatus

KW - Microbial biotransformation

KW - Silkworm

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Novel aromatics bearing 4-O-methylglucose unit isolated from the oriental crude drug Bombyx Batryticatus

Abstract

Keywords

ASJC Scopus subject areas

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