Novel monitoring of corneal surface hydration during photorefractive keratectomy using pulsed photothermal radiometry: In vitro study

Satoko Kawauchi, Hiroko Matsuyama, Minoru Obara, Miya Yoshikawa, Tsunenori Arai, Makoto Kikuchi, Masayoshi Katoh

Research output: Contribution to journalConference article


We developed novel monitoring methodology for corneal surface hydration during photorefractive keratectomy (PRK) in order to solve undercorrection issue at the central part of cornea (Central island). We employed pulsed photothermal radiometry to monitor corneal surface hydration. We performed two experiments; gelatin gel experiments and porcine cornea experiments in vitro. In the case of the gelatin gel experiments, the e-folding decay time of transient infrared radiation waveform from the ArF laser irradiated surface was prolonged from 420 μs to 30 ms with decreasing gelatin density from 15% to 0.15%. These measured e-folding decay times were good agreements with theoretical calculations. Using porcine cornea, we observed the e-folding decay time increase during the series of ArF excimer laser irradiations. Our method may be available to know ablation efficiency change to improve the controllability of refractive correction on the PRK.

Original languageEnglish
Pages (from-to)30-34
Number of pages5
JournalProceedings of SPIE - The International Society for Optical Engineering
Publication statusPublished - 1997 Dec 1
EventOphthalmic Technologies VII - San Jose, CA, United States
Duration: 1997 Feb 81997 Feb 8


  • Central island
  • Cornea
  • Hydration
  • Photorefractive keratectomy
  • Pulsed photothermal radiometry

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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