Novel monoterpene lactones from Cinnamomum inunctum

Hiroyuki Fuchino, Aya Yazawa, Fumiyuki Kiuchi, Nobuo Kawahara, Yutaka Takahashi, Motoyoshi Satake

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Four new monoterpene lactones, 5-(2,3-dihydroxy-3-methylbutyl)-4-hydroxy-4-methyldihydrofuran-2(3H)-one (1), 5-(2,3-dihydroxy-3-methylbutyl)-4-methylfuran-2(5H)-one (2), 8-hydroxy-4,7,7-trimethyl-1,6-dioxaspiro[4.4]non-3-en-2-one (3) and 8-hydroxy-4,7,7-trimethyl-1,6-dioxaspiro[4.4]non-3-en-2-one (4), were isolated from the methanolic extract of the fruit of Cinnamomum inunctum, a folk medicine in Myanmar, together with a known compound, 3-hydroxy-4,4-dimethyl-4-butyrolactone (5). Their chemical structures were determined by spectral methods. Among these, 3 and 4 possessed unique spirolactone moieties.

Original languageEnglish
Pages (from-to)833-836
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume63
Issue number10
Publication statusPublished - 2015 Oct 1

Fingerprint

Cinnamomum
4-Butyrolactone
Myanmar
Monoterpenes
Spironolactone
Traditional Medicine
Lactones
Fruits
Medicine
Fruit
2-methylfuran

Keywords

  • Cinnamomum inunctum
  • Lauraceae
  • Monoterpene

ASJC Scopus subject areas

  • Drug Discovery
  • Chemistry(all)

Cite this

Fuchino, H., Yazawa, A., Kiuchi, F., Kawahara, N., Takahashi, Y., & Satake, M. (2015). Novel monoterpene lactones from Cinnamomum inunctum. Chemical and Pharmaceutical Bulletin, 63(10), 833-836.

Novel monoterpene lactones from Cinnamomum inunctum. / Fuchino, Hiroyuki; Yazawa, Aya; Kiuchi, Fumiyuki; Kawahara, Nobuo; Takahashi, Yutaka; Satake, Motoyoshi.

In: Chemical and Pharmaceutical Bulletin, Vol. 63, No. 10, 01.10.2015, p. 833-836.

Research output: Contribution to journalArticle

Fuchino, H, Yazawa, A, Kiuchi, F, Kawahara, N, Takahashi, Y & Satake, M 2015, 'Novel monoterpene lactones from Cinnamomum inunctum', Chemical and Pharmaceutical Bulletin, vol. 63, no. 10, pp. 833-836.
Fuchino H, Yazawa A, Kiuchi F, Kawahara N, Takahashi Y, Satake M. Novel monoterpene lactones from Cinnamomum inunctum. Chemical and Pharmaceutical Bulletin. 2015 Oct 1;63(10):833-836.
Fuchino, Hiroyuki ; Yazawa, Aya ; Kiuchi, Fumiyuki ; Kawahara, Nobuo ; Takahashi, Yutaka ; Satake, Motoyoshi. / Novel monoterpene lactones from Cinnamomum inunctum. In: Chemical and Pharmaceutical Bulletin. 2015 ; Vol. 63, No. 10. pp. 833-836.
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