Novel monoterpene lactones from Cinnamomum inunctum

Hiroyuki Fuchino, Aya Yazawa, Fumiyuki Kiuchi, Nobuo Kawahara, Yutaka Takahashi, Motoyoshi Satake

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Four new monoterpene lactones, 5-(2,3-dihydroxy-3-methylbutyl)-4-hydroxy-4-methyldihydrofuran-2(3H)-one (1), 5-(2,3-dihydroxy-3-methylbutyl)-4-methylfuran-2(5H)-one (2), 8-hydroxy-4,7,7-trimethyl-1,6-dioxaspiro[4.4]non-3-en-2-one (3) and 8-hydroxy-4,7,7-trimethyl-1,6-dioxaspiro[4.4]non-3-en-2-one (4), were isolated from the methanolic extract of the fruit of Cinnamomum inunctum, a folk medicine in Myanmar, together with a known compound, 3-hydroxy-4,4-dimethyl-4-butyrolactone (5). Their chemical structures were determined by spectral methods. Among these, 3 and 4 possessed unique spirolactone moieties.

Original languageEnglish
Pages (from-to)833-836
Number of pages4
JournalChemical and Pharmaceutical Bulletin
Volume63
Issue number10
Publication statusPublished - 2015 Oct 1

Keywords

  • Cinnamomum inunctum
  • Lauraceae
  • Monoterpene

ASJC Scopus subject areas

  • Drug Discovery
  • Chemistry(all)

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