Novel Polyvinyl alcohoD-Degrading Enzyme and the Degradation Mechanism

Shuichi Matsumura, Noriyasu Tomizawa, Atsuko Toki, Kimihito Nishikawa, Kazunobu Toshima

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119 Citations (Scopus)

Abstract

A novel poly(vinyl alcohol) (PVA) degradation pathway was demonstrated such that the hydroxy group of PVA was first dehydrogenated into the corresponding carbonyl group to form the β-hydroxy ketone moiety which was followed by the aldolase-type cleavage to produce the methyl ketone and the aldehyde terminals by the PVA-assimilating strain, Alcaligenes faecalis KK314. Both the biodégradation steps of dehydrogenation and subsequent aldolase-type cleavage were catalyzed by the same protein having 67 kDa as the holoenzyme and apoenzyme of PVA dehydrogenase, respectively.

Original languageEnglish
Pages (from-to)7753-7761
Number of pages9
JournalMacromolecules
Volume32
Issue number23
Publication statusPublished - 1999 Dec 1

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Inorganic Chemistry
  • Materials Chemistry

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    Matsumura, S., Tomizawa, N., Toki, A., Nishikawa, K., & Toshima, K. (1999). Novel Polyvinyl alcohoD-Degrading Enzyme and the Degradation Mechanism. Macromolecules, 32(23), 7753-7761.