Numerical modeling of photon migration in the cerebral cortex of the living rat using the radiative transport equation

Hiroyuki Fujii, Shinpei Okawa, Ken Nadamoto, Eiji Okada, Yukio Yamada, Yoko Hoshi, Masao Watanabe

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Citation (Scopus)

Abstract

Accurate modeling and efficient calculation of photon migration in biological tissues is requested for determination of the optical properties of living tissues by in vivo experiments. This study develops a calculation scheme of photon migration for determination of the optical properties of the rat cerebral cortex (ca 0.2 cm thick) based on the three-dimensional time-dependent radiative transport equation assuming a homogeneous object. It is shown that the time-resolved profiles calculated by the developed scheme agree with the profiles measured by in vivo experiments using near infrared light. Also, an efficient calculation method is tested using the delta-Eddington approximation of the scattering phase function.

Original languageEnglish
Title of host publicationBiomedical Applications of Light Scattering IX
EditorsVadim Backman, Adam Wax
PublisherSPIE
ISBN (Electronic)9781628414233
DOIs
Publication statusPublished - 2015 Jan 1
EventBiomedical Applications of Light Scattering IX - San Francisco, United States
Duration: 2015 Feb 72015 Feb 8

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9333
ISSN (Print)1605-7422

Other

OtherBiomedical Applications of Light Scattering IX
CountryUnited States
CitySan Francisco
Period15/2/715/2/8

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Keywords

  • Optical properties
  • diffuse optical tomography
  • inverse analysis
  • radiative transport equation

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

Cite this

Fujii, H., Okawa, S., Nadamoto, K., Okada, E., Yamada, Y., Hoshi, Y., & Watanabe, M. (2015). Numerical modeling of photon migration in the cerebral cortex of the living rat using the radiative transport equation. In V. Backman, & A. Wax (Eds.), Biomedical Applications of Light Scattering IX [933313] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9333). SPIE. https://doi.org/10.1117/12.2079265