Numerical modeling of photon migration in the cerebral cortex of the living rat using the radiative transport equation

Hiroyuki Fujii, Shinpei Okawa, Ken Nadamoto, Eiji Okada, Yukio Yamada, Yoko Hoshi, Masao Watanabe

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    1 Citation (Scopus)

    Abstract

    Accurate modeling and efficient calculation of photon migration in biological tissues is requested for determination of the optical properties of living tissues by in vivo experiments. This study develops a calculation scheme of photon migration for determination of the optical properties of the rat cerebral cortex (ca 0.2 cm thick) based on the three-dimensional time-dependent radiative transport equation assuming a homogeneous object. It is shown that the time-resolved profiles calculated by the developed scheme agree with the profiles measured by in vivo experiments using near infrared light. Also, an efficient calculation method is tested using the delta-Eddington approximation of the scattering phase function.

    Original languageEnglish
    Title of host publicationBiomedical Applications of Light Scattering IX
    EditorsVadim Backman, Adam Wax
    PublisherSPIE
    ISBN (Electronic)9781628414233
    DOIs
    Publication statusPublished - 2015 Jan 1
    EventBiomedical Applications of Light Scattering IX - San Francisco, United States
    Duration: 2015 Feb 72015 Feb 8

    Publication series

    NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
    Volume9333
    ISSN (Print)1605-7422

    Other

    OtherBiomedical Applications of Light Scattering IX
    CountryUnited States
    CitySan Francisco
    Period15/2/715/2/8

    Keywords

    • Optical properties
    • diffuse optical tomography
    • inverse analysis
    • radiative transport equation

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Biomaterials
    • Atomic and Molecular Physics, and Optics
    • Radiology Nuclear Medicine and imaging

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  • Cite this

    Fujii, H., Okawa, S., Nadamoto, K., Okada, E., Yamada, Y., Hoshi, Y., & Watanabe, M. (2015). Numerical modeling of photon migration in the cerebral cortex of the living rat using the radiative transport equation. In V. Backman, & A. Wax (Eds.), Biomedical Applications of Light Scattering IX [933313] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9333). SPIE. https://doi.org/10.1117/12.2079265