Numerical study on the morphology and mechanical role of healthy and osteoporotic vertebral trabecular bone

Yuto Yoshiwara, Miguel Clanche, Khairul Salleh Basaruddin, Naoki Takano, Takayoshi Nakano

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

This study presents a numerical methodology to clarify the morphology of complex trabecular network architecture in human lumbar vertebra by means of the new post-processing technique for calculated microscopic stress by the homogenization method. Micro-CT image-based modeling technique is used and careful but intuitive and easy-to-use method for microstructure model, in other words region of interest (ROI), is also presented. The macroscopic homogenized properties that include not only the Young's moduli but also shear moduli could explain the difference of morphology between healthy and osteoporotic bones. This paper focuses on the change of degree of anisotropy. Then, the microscopic stress under three basis load cases was analyzed. In this analysis, the homogenization method has a merit in the computational cost. The trabeculae are classified into eight groups from the viewpoint of load bearing function against three loading conditions in the proposed post-processing of numerical results. It contributes to the understanding of the mechanical role of trabecular bone in vertebra. The primary trabecular bone that has been supposed to support the self-weight and secondary bone that connects the primary bone are successfully visualized. The discussion on the mechanical role of plate-like trabecular bone in the load path network system is also highlighted.

Original languageEnglish
Pages (from-to)270-285
Number of pages16
JournalJournal of Biomechanical Science and Engineering
Volume6
Issue number4
DOIs
Publication statusPublished - 2011

Fingerprint

Bone
Homogenization method
Bearings (structural)
Elastic moduli
Complex networks
Processing
Network architecture
Loads (forces)
Anisotropy
Microstructure
Costs

Keywords

  • Homogenization method
  • Microsccopic stress
  • Numerical analysis
  • Trabecular bone
  • Vertebra

ASJC Scopus subject areas

  • Biomedical Engineering

Cite this

Numerical study on the morphology and mechanical role of healthy and osteoporotic vertebral trabecular bone. / Yoshiwara, Yuto; Clanche, Miguel; Basaruddin, Khairul Salleh; Takano, Naoki; Nakano, Takayoshi.

In: Journal of Biomechanical Science and Engineering, Vol. 6, No. 4, 2011, p. 270-285.

Research output: Contribution to journalArticle

Yoshiwara, Yuto ; Clanche, Miguel ; Basaruddin, Khairul Salleh ; Takano, Naoki ; Nakano, Takayoshi. / Numerical study on the morphology and mechanical role of healthy and osteoporotic vertebral trabecular bone. In: Journal of Biomechanical Science and Engineering. 2011 ; Vol. 6, No. 4. pp. 270-285.
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