Abstract
Purpose: Dementia is a growing health problem for countries with aging populations, but few effective dementia treatments are available. However, there is increasing interest in oral health as a modifiable risk factor in interventions to prevent cognitive decline. This study aimed to investigate the impact of oral health on the decline of cognitive function over 3 years among Japanese people aged 70 and 80 years. Methods: Participants (n = 860) were community-dwelling older adults who participated in baseline and follow-up surveys (at baseline: 69–71 years n = 423; 79–81 years, n = 437). Registered dentists examined the number of teeth, number of functional teeth, number of periodontal teeth, and occlusal force. The Japanese version of the Montreal Cognitive Assessment was used to evaluate cognitive function. We also evaluated socioeconomic factors, medical history, drinking and smoking habits, physical performance, genetic factors, and C-reactive protein concentration in blood. A generalized estimating equation (GEE) was used to examine how oral health at baseline influenced cognitive decline over 3 years. Results: The GEE showed that the number of teeth (non-standardized coefficient: B = 0.031, p = 0.022) and occlusal force (B = 0.103, p = 0.004) at baseline were associated with cognitive function at follow-up, even after adjusting for other risk factors. Furthermore, maintaining more teeth (B = 0.009, p = 0.004) and a stronger occlusal force (B = 0.020, p = 0.040) buffered cognitive decline. Conclusions: Number of teeth and occlusal force predict cognitive decline over 3 subsequent years in Japanese older adults aged 70 and 80 years.
| Original language | English |
|---|---|
| Journal | Journal of Prosthodontic Research |
| DOIs | |
| Publication status | Accepted/In press - 2019 Jan 1 |
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Keywords
- Cognitive decline
- Cohort study
- Gerodontology
- Occlusal force
ASJC Scopus subject areas
- Oral Surgery
- Dentistry (miscellaneous)
Cite this
Occlusal force predicted cognitive decline among 70- and 80-year-old Japanese : A 3-year prospective cohort study. / Hatta, Kodai; Gondo, Yasuyuki; Kamide, Kei; Masui, Yukie; Inagaki, Hiroki; Nakagawa, Takeshi; Matsuda, Ken ichi; Inomata, Chisato; Takeshita, Hajime; Mihara, Yusuke; Fukutake, Motoyoshi; Kitamura, Masahiro; Murakami, Shinya; Kabayama, Mai; Ishizaki, Tatsuro; Arai, Yasumichi; Sugimoto, Ken; Rakugi, Hiromi; Maeda, Yoshinobu; Ikebe, Kazunori.
In: Journal of Prosthodontic Research, 01.01.2019.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Occlusal force predicted cognitive decline among 70- and 80-year-old Japanese
T2 - A 3-year prospective cohort study
AU - Hatta, Kodai
AU - Gondo, Yasuyuki
AU - Kamide, Kei
AU - Masui, Yukie
AU - Inagaki, Hiroki
AU - Nakagawa, Takeshi
AU - Matsuda, Ken ichi
AU - Inomata, Chisato
AU - Takeshita, Hajime
AU - Mihara, Yusuke
AU - Fukutake, Motoyoshi
AU - Kitamura, Masahiro
AU - Murakami, Shinya
AU - Kabayama, Mai
AU - Ishizaki, Tatsuro
AU - Arai, Yasumichi
AU - Sugimoto, Ken
AU - Rakugi, Hiromi
AU - Maeda, Yoshinobu
AU - Ikebe, Kazunori
PY - 2019/1/1
Y1 - 2019/1/1
N2 - Purpose: Dementia is a growing health problem for countries with aging populations, but few effective dementia treatments are available. However, there is increasing interest in oral health as a modifiable risk factor in interventions to prevent cognitive decline. This study aimed to investigate the impact of oral health on the decline of cognitive function over 3 years among Japanese people aged 70 and 80 years. Methods: Participants (n = 860) were community-dwelling older adults who participated in baseline and follow-up surveys (at baseline: 69–71 years n = 423; 79–81 years, n = 437). Registered dentists examined the number of teeth, number of functional teeth, number of periodontal teeth, and occlusal force. The Japanese version of the Montreal Cognitive Assessment was used to evaluate cognitive function. We also evaluated socioeconomic factors, medical history, drinking and smoking habits, physical performance, genetic factors, and C-reactive protein concentration in blood. A generalized estimating equation (GEE) was used to examine how oral health at baseline influenced cognitive decline over 3 years. Results: The GEE showed that the number of teeth (non-standardized coefficient: B = 0.031, p = 0.022) and occlusal force (B = 0.103, p = 0.004) at baseline were associated with cognitive function at follow-up, even after adjusting for other risk factors. Furthermore, maintaining more teeth (B = 0.009, p = 0.004) and a stronger occlusal force (B = 0.020, p = 0.040) buffered cognitive decline. Conclusions: Number of teeth and occlusal force predict cognitive decline over 3 subsequent years in Japanese older adults aged 70 and 80 years.
AB - Purpose: Dementia is a growing health problem for countries with aging populations, but few effective dementia treatments are available. However, there is increasing interest in oral health as a modifiable risk factor in interventions to prevent cognitive decline. This study aimed to investigate the impact of oral health on the decline of cognitive function over 3 years among Japanese people aged 70 and 80 years. Methods: Participants (n = 860) were community-dwelling older adults who participated in baseline and follow-up surveys (at baseline: 69–71 years n = 423; 79–81 years, n = 437). Registered dentists examined the number of teeth, number of functional teeth, number of periodontal teeth, and occlusal force. The Japanese version of the Montreal Cognitive Assessment was used to evaluate cognitive function. We also evaluated socioeconomic factors, medical history, drinking and smoking habits, physical performance, genetic factors, and C-reactive protein concentration in blood. A generalized estimating equation (GEE) was used to examine how oral health at baseline influenced cognitive decline over 3 years. Results: The GEE showed that the number of teeth (non-standardized coefficient: B = 0.031, p = 0.022) and occlusal force (B = 0.103, p = 0.004) at baseline were associated with cognitive function at follow-up, even after adjusting for other risk factors. Furthermore, maintaining more teeth (B = 0.009, p = 0.004) and a stronger occlusal force (B = 0.020, p = 0.040) buffered cognitive decline. Conclusions: Number of teeth and occlusal force predict cognitive decline over 3 subsequent years in Japanese older adults aged 70 and 80 years.
KW - Cognitive decline
KW - Cohort study
KW - Gerodontology
KW - Occlusal force
UR - http://www.scopus.com/inward/record.url?scp=85074537345&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85074537345&partnerID=8YFLogxK
U2 - 10.1016/j.jpor.2019.07.002
DO - 10.1016/j.jpor.2019.07.002
M3 - Article
AN - SCOPUS:85074537345
JO - Journal of Prosthodontic Research
JF - Journal of Prosthodontic Research
SN - 1883-1958
ER -