Ocular manifestation of bullous and cicatricial pemphigoid

Shin Hatou, Motoko Kawashima, Masataka Kawai, Yukihiko Mashima, Yoshihisa Oguchi, Masakazu Yamada, Aiko Tanigawa, Masayuki Amagai

Research output: Contribution to journalArticle

Abstract

Purpose: Pemphigoid is classified into 2 types, bullous pemphigoid (BP) and cicatricial pemphigoid (CP), depending on the target antigen. We investigated ocular manifestations for each type of pemphigoid. Methods: Clinical records of definitive pemphigoid cases diagnosed by the Department of Dermatology, Keio University Hospital were retrospectively reviewed. Results: Ninety-five cases (BP, 83 cases: CP, 12 cases) were recruited. In 23 (27.7%) of the BP cases and 11 (91.7%) of the CP cases, ophthalmological examination was performed. In 18 cases of the 23 BP cases, various ocular diseases (cataract, 10 cases: keratoconjunctivitis, 8 cases: glaucoma, 4 cases: miscellaneous, 6 cases; allowing double-counting) were found, but no case was associated with ocular cicatricial pemphigoid (OCP). In contrast, OCP of various stages (stage 2, 1 eye: stage 3, 10 eyes, stage 4, 5 eyes; Foster's grading) was found in 8 of the 11 CP cases. Conclusions: CP but not BP is frequently associated with OCP. Most of ocular complications in BP are presumed to be due to corticosteroid medication.

Original languageEnglish
Pages (from-to)374-377
Number of pages4
JournalFolia Ophthalmologica Japonica
Volume55
Issue number5
Publication statusPublished - 2004

Fingerprint

Eye Manifestations
Benign Mucous Membrane Pemphigoid
Bullous Pemphigoid
Keratoconjunctivitis
Eye Diseases
Dermatology
Glaucoma
Cataract
Adrenal Cortex Hormones

Keywords

  • Bullous Pemphigoid
  • Cicatricial Pemphigoid
  • Ocular Cicatricial Pemphigoid

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Hatou, S., Kawashima, M., Kawai, M., Mashima, Y., Oguchi, Y., Yamada, M., ... Amagai, M. (2004). Ocular manifestation of bullous and cicatricial pemphigoid. Folia Ophthalmologica Japonica, 55(5), 374-377.

Ocular manifestation of bullous and cicatricial pemphigoid. / Hatou, Shin; Kawashima, Motoko; Kawai, Masataka; Mashima, Yukihiko; Oguchi, Yoshihisa; Yamada, Masakazu; Tanigawa, Aiko; Amagai, Masayuki.

In: Folia Ophthalmologica Japonica, Vol. 55, No. 5, 2004, p. 374-377.

Research output: Contribution to journalArticle

Hatou, S, Kawashima, M, Kawai, M, Mashima, Y, Oguchi, Y, Yamada, M, Tanigawa, A & Amagai, M 2004, 'Ocular manifestation of bullous and cicatricial pemphigoid', Folia Ophthalmologica Japonica, vol. 55, no. 5, pp. 374-377.
Hatou S, Kawashima M, Kawai M, Mashima Y, Oguchi Y, Yamada M et al. Ocular manifestation of bullous and cicatricial pemphigoid. Folia Ophthalmologica Japonica. 2004;55(5):374-377.
Hatou, Shin ; Kawashima, Motoko ; Kawai, Masataka ; Mashima, Yukihiko ; Oguchi, Yoshihisa ; Yamada, Masakazu ; Tanigawa, Aiko ; Amagai, Masayuki. / Ocular manifestation of bullous and cicatricial pemphigoid. In: Folia Ophthalmologica Japonica. 2004 ; Vol. 55, No. 5. pp. 374-377.
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