Abstract
Purpose: Pemphigoid is classified into 2 types, bullous pemphigoid (BP) and cicatricial pemphigoid (CP), depending on the target antigen. We investigated ocular manifestations for each type of pemphigoid. Methods: Clinical records of definitive pemphigoid cases diagnosed by the Department of Dermatology, Keio University Hospital were retrospectively reviewed. Results: Ninety-five cases (BP, 83 cases: CP, 12 cases) were recruited. In 23 (27.7%) of the BP cases and 11 (91.7%) of the CP cases, ophthalmological examination was performed. In 18 cases of the 23 BP cases, various ocular diseases (cataract, 10 cases: keratoconjunctivitis, 8 cases: glaucoma, 4 cases: miscellaneous, 6 cases; allowing double-counting) were found, but no case was associated with ocular cicatricial pemphigoid (OCP). In contrast, OCP of various stages (stage 2, 1 eye: stage 3, 10 eyes, stage 4, 5 eyes; Foster's grading) was found in 8 of the 11 CP cases. Conclusions: CP but not BP is frequently associated with OCP. Most of ocular complications in BP are presumed to be due to corticosteroid medication.
| Original language | English |
|---|---|
| Pages (from-to) | 374-377 |
| Number of pages | 4 |
| Journal | Folia Ophthalmologica Japonica |
| Volume | 55 |
| Issue number | 5 |
| Publication status | Published - 2004 |
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Keywords
- Bullous Pemphigoid
- Cicatricial Pemphigoid
- Ocular Cicatricial Pemphigoid
ASJC Scopus subject areas
- Ophthalmology
Cite this
Ocular manifestation of bullous and cicatricial pemphigoid. / Hatou, Shin; Kawashima, Motoko; Kawai, Masataka; Mashima, Yukihiko; Oguchi, Yoshihisa; Yamada, Masakazu; Tanigawa, Aiko; Amagai, Masayuki.
In: Folia Ophthalmologica Japonica, Vol. 55, No. 5, 2004, p. 374-377.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ocular manifestation of bullous and cicatricial pemphigoid
AU - Hatou, Shin
AU - Kawashima, Motoko
AU - Kawai, Masataka
AU - Mashima, Yukihiko
AU - Oguchi, Yoshihisa
AU - Yamada, Masakazu
AU - Tanigawa, Aiko
AU - Amagai, Masayuki
PY - 2004
Y1 - 2004
N2 - Purpose: Pemphigoid is classified into 2 types, bullous pemphigoid (BP) and cicatricial pemphigoid (CP), depending on the target antigen. We investigated ocular manifestations for each type of pemphigoid. Methods: Clinical records of definitive pemphigoid cases diagnosed by the Department of Dermatology, Keio University Hospital were retrospectively reviewed. Results: Ninety-five cases (BP, 83 cases: CP, 12 cases) were recruited. In 23 (27.7%) of the BP cases and 11 (91.7%) of the CP cases, ophthalmological examination was performed. In 18 cases of the 23 BP cases, various ocular diseases (cataract, 10 cases: keratoconjunctivitis, 8 cases: glaucoma, 4 cases: miscellaneous, 6 cases; allowing double-counting) were found, but no case was associated with ocular cicatricial pemphigoid (OCP). In contrast, OCP of various stages (stage 2, 1 eye: stage 3, 10 eyes, stage 4, 5 eyes; Foster's grading) was found in 8 of the 11 CP cases. Conclusions: CP but not BP is frequently associated with OCP. Most of ocular complications in BP are presumed to be due to corticosteroid medication.
AB - Purpose: Pemphigoid is classified into 2 types, bullous pemphigoid (BP) and cicatricial pemphigoid (CP), depending on the target antigen. We investigated ocular manifestations for each type of pemphigoid. Methods: Clinical records of definitive pemphigoid cases diagnosed by the Department of Dermatology, Keio University Hospital were retrospectively reviewed. Results: Ninety-five cases (BP, 83 cases: CP, 12 cases) were recruited. In 23 (27.7%) of the BP cases and 11 (91.7%) of the CP cases, ophthalmological examination was performed. In 18 cases of the 23 BP cases, various ocular diseases (cataract, 10 cases: keratoconjunctivitis, 8 cases: glaucoma, 4 cases: miscellaneous, 6 cases; allowing double-counting) were found, but no case was associated with ocular cicatricial pemphigoid (OCP). In contrast, OCP of various stages (stage 2, 1 eye: stage 3, 10 eyes, stage 4, 5 eyes; Foster's grading) was found in 8 of the 11 CP cases. Conclusions: CP but not BP is frequently associated with OCP. Most of ocular complications in BP are presumed to be due to corticosteroid medication.
KW - Bullous Pemphigoid
KW - Cicatricial Pemphigoid
KW - Ocular Cicatricial Pemphigoid
UR - http://www.scopus.com/inward/record.url?scp=3843117521&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=3843117521&partnerID=8YFLogxK
M3 - Article
VL - 55
SP - 374
EP - 377
JO - Folia Ophthalmologica Japonica
JF - Folia Ophthalmologica Japonica
SN - 0015-5667
IS - 5
ER -