Ocular surface management in corneal transplantation, a review

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Purpose: To discuss the importance of ocular surface management in corneal transplantation, especially in limbal transplantation. Methods: Since the corneal epithelium is not completely recovered after corneal transplantation, meticulous attention should be paid to the ocular surface to prevent infection and rejection, which are the major causes of corneal transplantation failure. Preoperative evaluations of the ocular surface should be carried out, followed by appropriate surgical procedures, depending on the condition of each patient. Vigorous immunosuppressive measures should be taken after surgery. Results: In both case reports presented in this study, each patient underwent successful surgery and his condition was controlled by medication suited to his needs. Conclusions: For those patients with stem cell deficiency, limbal transplantation, possibly with the use of autologous serum drops, should be considered to reconstruct and maintain the ocular surface. Ocular surface management is necessary for the success of corneal transplantation, especially for limbal transplantation.

Original languageEnglish
Pages (from-to)502-508
Number of pages7
JournalJapanese Journal of Ophthalmology
Volume43
Issue number6
DOIs
Publication statusPublished - 1999 Nov
Externally publishedYes

Fingerprint

Corneal Transplantation
Transplantation
Corneal Epithelium
Immunosuppressive Agents
Stem Cells
Infection
Serum

Keywords

  • Autologous serum
  • Corneal transplantation
  • Ocular surface management

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Ocular surface management in corneal transplantation, a review. / Tsubota, Kazuo.

In: Japanese Journal of Ophthalmology, Vol. 43, No. 6, 11.1999, p. 502-508.

Research output: Contribution to journalArticle

@article{15bd53869f7f4436b9c58217cd8aedb9,
title = "Ocular surface management in corneal transplantation, a review",
abstract = "Purpose: To discuss the importance of ocular surface management in corneal transplantation, especially in limbal transplantation. Methods: Since the corneal epithelium is not completely recovered after corneal transplantation, meticulous attention should be paid to the ocular surface to prevent infection and rejection, which are the major causes of corneal transplantation failure. Preoperative evaluations of the ocular surface should be carried out, followed by appropriate surgical procedures, depending on the condition of each patient. Vigorous immunosuppressive measures should be taken after surgery. Results: In both case reports presented in this study, each patient underwent successful surgery and his condition was controlled by medication suited to his needs. Conclusions: For those patients with stem cell deficiency, limbal transplantation, possibly with the use of autologous serum drops, should be considered to reconstruct and maintain the ocular surface. Ocular surface management is necessary for the success of corneal transplantation, especially for limbal transplantation.",
keywords = "Autologous serum, Corneal transplantation, Ocular surface management",
author = "Kazuo Tsubota",
year = "1999",
month = "11",
doi = "10.1016/S0021-5155(99)00140-9",
language = "English",
volume = "43",
pages = "502--508",
journal = "Japanese Journal of Ophthalmology",
issn = "0021-5155",
publisher = "Springer Japan",
number = "6",

}

TY - JOUR

T1 - Ocular surface management in corneal transplantation, a review

AU - Tsubota, Kazuo

PY - 1999/11

Y1 - 1999/11

N2 - Purpose: To discuss the importance of ocular surface management in corneal transplantation, especially in limbal transplantation. Methods: Since the corneal epithelium is not completely recovered after corneal transplantation, meticulous attention should be paid to the ocular surface to prevent infection and rejection, which are the major causes of corneal transplantation failure. Preoperative evaluations of the ocular surface should be carried out, followed by appropriate surgical procedures, depending on the condition of each patient. Vigorous immunosuppressive measures should be taken after surgery. Results: In both case reports presented in this study, each patient underwent successful surgery and his condition was controlled by medication suited to his needs. Conclusions: For those patients with stem cell deficiency, limbal transplantation, possibly with the use of autologous serum drops, should be considered to reconstruct and maintain the ocular surface. Ocular surface management is necessary for the success of corneal transplantation, especially for limbal transplantation.

AB - Purpose: To discuss the importance of ocular surface management in corneal transplantation, especially in limbal transplantation. Methods: Since the corneal epithelium is not completely recovered after corneal transplantation, meticulous attention should be paid to the ocular surface to prevent infection and rejection, which are the major causes of corneal transplantation failure. Preoperative evaluations of the ocular surface should be carried out, followed by appropriate surgical procedures, depending on the condition of each patient. Vigorous immunosuppressive measures should be taken after surgery. Results: In both case reports presented in this study, each patient underwent successful surgery and his condition was controlled by medication suited to his needs. Conclusions: For those patients with stem cell deficiency, limbal transplantation, possibly with the use of autologous serum drops, should be considered to reconstruct and maintain the ocular surface. Ocular surface management is necessary for the success of corneal transplantation, especially for limbal transplantation.

KW - Autologous serum

KW - Corneal transplantation

KW - Ocular surface management

UR - http://www.scopus.com/inward/record.url?scp=0032714635&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0032714635&partnerID=8YFLogxK

U2 - 10.1016/S0021-5155(99)00140-9

DO - 10.1016/S0021-5155(99)00140-9

M3 - Article

VL - 43

SP - 502

EP - 508

JO - Japanese Journal of Ophthalmology

JF - Japanese Journal of Ophthalmology

SN - 0021-5155

IS - 6

ER -