Ocular surface reconstruction update

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Ocular surface reconstruction (OSR) is now a standard procedure in the treatment of severe ocular surface disorders. The past few years have revealed the long-term results of patients who were operated on during the early stages of OSR development, and we now have a more realistic view of the benefits and limits of the procedure. On the other hand, further understanding of the physiologic role played by the amniotic membrane (AM) has opened doors to further refined techniques in treating these patients. This review will introduce some of the major contributions made during the past years in the advancement of OSR. Clinically, we are at a stage of reviewing the pros and cons of the various transplantation techniques. Identification of factors crucial for a successful OSR procedure will further improve surgical results. Basic researchers are on the verge of identifying the so-called limbal stem cells, and further understanding of AM physiology will lead the way to tissue engineering techniques as another alternative in OSR surgery.

Original languageEnglish
Pages (from-to)213-219
Number of pages7
JournalCurrent Opinion in Ophthalmology
Volume13
Issue number4
DOIs
Publication statusPublished - 2002 Aug
Externally publishedYes

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Amnion
Tissue Engineering
Stem Cells
Transplantation
Research Personnel
Therapeutics

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Ocular surface reconstruction update. / Shimmura, Shigeto; Tsubota, Kazuo.

In: Current Opinion in Ophthalmology, Vol. 13, No. 4, 08.2002, p. 213-219.

Research output: Contribution to journalArticle

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