Odobromoamide, a terminal alkynyl bromide-containing cyclodepsipeptide from the marine cyanobacterium okeania sp.

Kosuke Sueyoshi, Takafumi Kudo, Aki Yamano, Shimpei Sumimoto, Arihiro Iwasaki, Kiyotake Suenaga, Toshiaki Teruya

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The bioassay-guided fractionation of the Okinawan marine cyanobacterium Okeania sp. led to the isolation of the novel cyclodepsipeptide odobromoamide (1). The gross structure of 1 was determined by spectroscopic analyses, and its absolute stereochemistry was determined using a variety of different methods, including chemical derivatization and degradation followed by HPLC analysis. In addition, odobromoamide (1) exhibited broad-spectrum cytotoxicity against a human cancer cell line panel.

Original languageEnglish
Pages (from-to)436-440
Number of pages5
JournalBulletin of the Chemical Society of Japan
Volume90
Issue number4
DOIs
Publication statusPublished - 2017

ASJC Scopus subject areas

  • Chemistry(all)

Fingerprint Dive into the research topics of 'Odobromoamide, a terminal alkynyl bromide-containing cyclodepsipeptide from the marine cyanobacterium okeania sp.'. Together they form a unique fingerprint.

  • Cite this