Odobromoamide, a terminal alkynyl bromide-containing cyclodepsipeptide from the marine cyanobacterium okeania sp.

Kosuke Sueyoshi, Takafumi Kudo, Aki Yamano, Shimpei Sumimoto, Arihiro Iwasaki, Kiyotake Suenaga, Toshiaki Teruya

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

The bioassay-guided fractionation of the Okinawan marine cyanobacterium Okeania sp. led to the isolation of the novel cyclodepsipeptide odobromoamide (1). The gross structure of 1 was determined by spectroscopic analyses, and its absolute stereochemistry was determined using a variety of different methods, including chemical derivatization and degradation followed by HPLC analysis. In addition, odobromoamide (1) exhibited broad-spectrum cytotoxicity against a human cancer cell line panel.

Original languageEnglish
Pages (from-to)436-440
Number of pages5
JournalBulletin of the Chemical Society of Japan
Volume90
Issue number4
DOIs
Publication statusPublished - 2017

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Depsipeptides
Stereochemistry
Bioassay
Cytotoxicity
Fractionation
Bromides
Cells
Degradation
Cyanobacteria

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Odobromoamide, a terminal alkynyl bromide-containing cyclodepsipeptide from the marine cyanobacterium okeania sp. / Sueyoshi, Kosuke; Kudo, Takafumi; Yamano, Aki; Sumimoto, Shimpei; Iwasaki, Arihiro; Suenaga, Kiyotake; Teruya, Toshiaki.

In: Bulletin of the Chemical Society of Japan, Vol. 90, No. 4, 2017, p. 436-440.

Research output: Contribution to journalArticle

Sueyoshi, Kosuke ; Kudo, Takafumi ; Yamano, Aki ; Sumimoto, Shimpei ; Iwasaki, Arihiro ; Suenaga, Kiyotake ; Teruya, Toshiaki. / Odobromoamide, a terminal alkynyl bromide-containing cyclodepsipeptide from the marine cyanobacterium okeania sp. In: Bulletin of the Chemical Society of Japan. 2017 ; Vol. 90, No. 4. pp. 436-440.
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AU - Teruya, Toshiaki

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