On-chip fragment-based approach for discovery of high-affinity bivalent inhibitors

Isao Miyazaki, Siro Simizu, Keisuke Ishida, Hiroyuki Osada

Research output: Contribution to journalArticle

6 Citations (Scopus)
Original languageEnglish
Pages (from-to)838-843
Number of pages6
JournalChemBioChem
Volume10
Issue number5
DOIs
Publication statusPublished - 2009 Mar 23
Externally publishedYes

Fingerprint

Tacrolimus Binding Protein 1A
Photochemistry
Protein Array Analysis
Peptide Fragments
Photochemical reactions
Tacrolimus
Drug Discovery
Structure-Activity Relationship
Immunosuppressive Agents
Molecular Structure
Protein Binding
Immobilization
Molecular structure
Ligands
Cell Line
Proteins

Keywords

  • Fragment combination array
  • Immobilization
  • Inhibitors
  • Photochemistry
  • Structure-activity relationships

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Molecular Medicine
  • Molecular Biology

Cite this

On-chip fragment-based approach for discovery of high-affinity bivalent inhibitors. / Miyazaki, Isao; Simizu, Siro; Ishida, Keisuke; Osada, Hiroyuki.

In: ChemBioChem, Vol. 10, No. 5, 23.03.2009, p. 838-843.

Research output: Contribution to journalArticle

Miyazaki, Isao ; Simizu, Siro ; Ishida, Keisuke ; Osada, Hiroyuki. / On-chip fragment-based approach for discovery of high-affinity bivalent inhibitors. In: ChemBioChem. 2009 ; Vol. 10, No. 5. pp. 838-843.
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