One-step syntheses of alkyl glycosides and alkyl-substituted DNA oligomers by chemoselective glycosidations using DNA bases

Yuichi Nishikubo, Kaname Sasaki, Shuichi Matsumura, Kazunobu Toshima

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

The simple and practical synthesis of alkyl glycosides by novel chemoselective glycosidations using natural resources, DNA and RNA nucleosides, was realized, and the one-step synthesis of chemoselectively modified DNA oligomers using the glycosidation method was also demonstrated.

Original languageEnglish
Pages (from-to)1041-1045
Number of pages5
JournalTetrahedron Letters
Volume47
Issue number7
DOIs
Publication statusPublished - 2006 Feb 13

Keywords

  • Alkyl glycoside
  • Carbohydrate
  • DNA
  • Glycosidation
  • Modified DNA oligomer
  • RNA

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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