One-year outcome after percutaneous coronary intervention for acute coronary syndrome ― An analysis of 20,042 patients from a Japanese nationwide registry

Mitsuaki Sawano, Shun Kohsaka, Hideki Ishii, Yohei Numasawa, Kyohei Yamaji, Taku Inohara, Tetsuya Amano, Yuji Ikari, Masato Nakamura

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Background: Acute coronary syndrome (ACS) hospital survivors experience a wide array of late adverse cardiac events, despite considerable advances in the quality of care. We investigated 30-day and 1-year outcomes of ACS hospital survivors using a Japanese nationwide cohort. Methods and Results: We studied 20,042 ACS patients who underwent percutaneous coronary intervention (PCI) in 2017: 10,242 (51%) with ST-elevation myocardial infarction (STEMI), 3,027 (15%) with non-ST-elevation myocardial infarction (NSTEMI), and 6,773 (34%) with unstable angina (UA). The mean (±SD) age was 69.6±12.4 years, 77% of the patients were men, and 20% had a previous history of PCI. The overall 30-day all-cause, cardiac, and non-cardiac mortality rates were 3.0%, 2.4%, and 0.6%, respectively. The overall 1-year incidence of all-cause, cardiac, and non-cardiac death was 7.1%, 4.2%, and 2.8%, respectively. Compared with UA patients, STEMI patients had a higher risk of all fatal events, non-fatal ischemic stroke, and acute heart failure, and NSTEMI patients had a higher risk of heart failure. Conclusions: The results from our ACS hospital survivor PCI database suggest the need to improve care for the acute myocardial infarction population to lessen the burden of 30-day mortality due to ACS, heart failure, and sudden cardiac death, as well as 1-year ischemic stroke and heart failure events.

Original languageEnglish
Pages (from-to)1756-1767
Number of pages12
JournalCirculation Journal
Volume85
Issue number10
DOIs
Publication statusPublished - 2021 Sep 24

Keywords

  • Acute coronary syndrome
  • Acute myocardial infarction
  • Mortality
  • Outcome
  • Percutaneous coronary intervention

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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