Onset of polymyositis with autoantibodies to threonyl-tRNA synthetase during pregnancy

M. Satoh, A. K. Ajmani, M. Hirakata, A. Suwa, J. B. Winfield, W. H. Reeves

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A 24-year-old black woman developed polymyositis with autoantibodies to threonyl-tRNA synthetase in the 2nd trimester of her 3rd pregnancy. This was complicated by fetal loss and the development of severe relapsing myositis resistant to corticosteroid and azathioprine therapy. These features were also common in other cases in the literature. Antisynthetase antibodies had not been reported in myositis occurring during pregnancy and may be of interest regarding the pathogenesis of inflammatory myopathy complicating pregnancy.

Original languageEnglish
Pages (from-to)1564-1566
Number of pages3
JournalJournal of Rheumatology
Volume21
Issue number8
Publication statusPublished - 1994 Jan 1
Externally publishedYes

Keywords

  • AMINOACYL-tRNA SYNTHETASE
  • POLYMYOSITIS
  • PREGNANCY
  • REACTIVATION OF VIRUSES

ASJC Scopus subject areas

  • Rheumatology
  • Immunology and Allergy
  • Immunology

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  • Cite this

    Satoh, M., Ajmani, A. K., Hirakata, M., Suwa, A., Winfield, J. B., & Reeves, W. H. (1994). Onset of polymyositis with autoantibodies to threonyl-tRNA synthetase during pregnancy. Journal of Rheumatology, 21(8), 1564-1566.