Onset of polymyositis with autoantibodies to threonyl-tRNA synthetase during pregnancy

M. Satoh, A. K. Ajmani, Michito Hirakata, A. Suwa, J. B. Winfield, W. H. Reeves

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

A 24-year-old black woman developed polymyositis with autoantibodies to threonyl-tRNA synthetase in the 2nd trimester of her 3rd pregnancy. This was complicated by fetal loss and the development of severe relapsing myositis resistant to corticosteroid and azathioprine therapy. These features were also common in other cases in the literature. Antisynthetase antibodies had not been reported in myositis occurring during pregnancy and may be of interest regarding the pathogenesis of inflammatory myopathy complicating pregnancy.

Original languageEnglish
Pages (from-to)1564-1566
Number of pages3
JournalJournal of Rheumatology
Volume21
Issue number8
Publication statusPublished - 1994
Externally publishedYes

Fingerprint

Threonine-tRNA Ligase
Polymyositis
Myositis
Autoantibodies
Pregnancy
Pregnancy Trimesters
Azathioprine
Fetal Development
Adrenal Cortex Hormones
Antibodies
Therapeutics

Keywords

  • AMINOACYL-tRNA SYNTHETASE
  • POLYMYOSITIS
  • PREGNANCY
  • REACTIVATION OF VIRUSES

ASJC Scopus subject areas

  • Immunology
  • Rheumatology

Cite this

Satoh, M., Ajmani, A. K., Hirakata, M., Suwa, A., Winfield, J. B., & Reeves, W. H. (1994). Onset of polymyositis with autoantibodies to threonyl-tRNA synthetase during pregnancy. Journal of Rheumatology, 21(8), 1564-1566.

Onset of polymyositis with autoantibodies to threonyl-tRNA synthetase during pregnancy. / Satoh, M.; Ajmani, A. K.; Hirakata, Michito; Suwa, A.; Winfield, J. B.; Reeves, W. H.

In: Journal of Rheumatology, Vol. 21, No. 8, 1994, p. 1564-1566.

Research output: Contribution to journalArticle

Satoh, M, Ajmani, AK, Hirakata, M, Suwa, A, Winfield, JB & Reeves, WH 1994, 'Onset of polymyositis with autoantibodies to threonyl-tRNA synthetase during pregnancy', Journal of Rheumatology, vol. 21, no. 8, pp. 1564-1566.
Satoh, M. ; Ajmani, A. K. ; Hirakata, Michito ; Suwa, A. ; Winfield, J. B. ; Reeves, W. H. / Onset of polymyositis with autoantibodies to threonyl-tRNA synthetase during pregnancy. In: Journal of Rheumatology. 1994 ; Vol. 21, No. 8. pp. 1564-1566.
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