A 24-year-old black woman developed polymyositis with autoantibodies to threonyl-tRNA synthetase in the 2nd trimester of her 3rd pregnancy. This was complicated by fetal loss and the development of severe relapsing myositis resistant to corticosteroid and azathioprine therapy. These features were also common in other cases in the literature. Antisynthetase antibodies had not been reported in myositis occurring during pregnancy and may be of interest regarding the pathogenesis of inflammatory myopathy complicating pregnancy.
|Number of pages||3|
|Journal||Journal of Rheumatology|
|Publication status||Published - 1994 Jan 1|
- AMINOACYL-tRNA SYNTHETASE
- REACTIVATION OF VIRUSES
ASJC Scopus subject areas
- Immunology and Allergy