Optical observation of DNA translocation dynamics through solid-state nanopores

Hirohito Yamazaki, Shintaro Itoh, Keiko Esashika, Toshiharu Saiki

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    We report an optical nanopore detection system for investigating DNA translocation dynamics through a nanopore at sub-millisecond and sub-100-nm resolutions. The proposed optical nanopore detection scheme enables the observation of both the translocation process and the escape process. We found different correlation between the translocation time and the escape time, depending on whether the translocation occurs in a folded or unfolded configuration.

    Original languageEnglish
    Title of host publication2015 11th Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2015
    PublisherInstitute of Electrical and Electronics Engineers Inc.
    ISBN (Electronic)9781467371094
    DOIs
    Publication statusPublished - 2016 Jan 7
    Event11th Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2015 - Busan, Korea, Republic of
    Duration: 2015 Aug 242015 Aug 28

    Publication series

    Name2015 11th Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2015
    Volume3

    Other

    Other11th Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2015
    CountryKorea, Republic of
    CityBusan
    Period15/8/2415/8/28

    ASJC Scopus subject areas

    • Electrical and Electronic Engineering
    • Atomic and Molecular Physics, and Optics

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  • Cite this

    Yamazaki, H., Itoh, S., Esashika, K., & Saiki, T. (2016). Optical observation of DNA translocation dynamics through solid-state nanopores. In 2015 11th Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2015 [7376422] (2015 11th Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2015; Vol. 3). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CLEOPR.2015.7376422