Optical observation of DNA translocation dynamics through solid-state nanopores

Hirohito Yamazaki, Shintaro Itoh, Keiko Esashika, Toshiharu Saiki

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We report an optical nanopore detection system for investigating DNA translocation dynamics through a nanopore at sub-millisecond and sub-100-nm resolutions. The proposed optical nanopore detection scheme enables the observation of both the translocation process and the escape process. We found different correlation between the translocation time and the escape time, depending on whether the translocation occurs in a folded or unfolded configuration.

Original languageEnglish
Title of host publication2015 11th Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2015
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Electronic)9781467371094
DOIs
Publication statusPublished - 2016 Jan 7
Event11th Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2015 - Busan, Korea, Republic of
Duration: 2015 Aug 242015 Aug 28

Publication series

Name2015 11th Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2015
Volume3

Other

Other11th Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2015
CountryKorea, Republic of
CityBusan
Period15/8/2415/8/28

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ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Atomic and Molecular Physics, and Optics

Cite this

Yamazaki, H., Itoh, S., Esashika, K., & Saiki, T. (2016). Optical observation of DNA translocation dynamics through solid-state nanopores. In 2015 11th Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2015 [7376422] (2015 11th Conference on Lasers and Electro-Optics Pacific Rim, CLEO-PR 2015; Vol. 3). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/CLEOPR.2015.7376422