Optical property change of blood on an optical window boundary by 660-nm band laser irradiation

Mei Takahashi, Arisa Ito, Tsunenori Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We studied an optical interaction on an optical window and blood boundary during the CW laser irradiation in 660 nm band until blood charring occurrence. We previously reported that a pre-charring optical behavior may be detected by diffuse-reflected-light power time-history. The aim of this study is to measure absorption coefficient (μ a) and reduced scattering coefficient (μ' s) of a blood model to explain this pre-charring optical behavior. The blood model sandwiched between 2 glass slides to simulate the interface between blood and the optical window was used. A double integrating sphere system was constructed. The red laser in 660 nm band was irradiated to the sandwiched blood model. Fourty W/cm 2 in irradiance was used as the maximum irradiance during irradiation via the laser catheter in vivo. μ a and μ' s in the irradiated laser wavelength were measured continuously until blood charring occurrence using inverse adding doubling analysis. Continuous μ a increase of 5-10% from the initial value until charring was observed. Decrease of μ' s with 8-10% during 15-30 s before charring following broad peak was obtained. We think these μ a and μ' s changes may explain the pre-charring optical behavior detected by the diffuse-reflected-light power time-history in our reported study.

Original languageEnglish
Title of host publicationProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume8221
DOIs
Publication statusPublished - 2012
EventOptical Interactions with Tissue and Cells XXIII - San Francisco, CA, United States
Duration: 2012 Jan 232012 Jan 25

Other

OtherOptical Interactions with Tissue and Cells XXIII
CountryUnited States
CitySan Francisco, CA
Period12/1/2312/1/25

Fingerprint

charring
Laser beam effects
blood
Lasers
Blood
Optical properties
optical properties
irradiation
lasers
irradiance
History
histories
occurrences
Light
Continuous wave lasers
Catheters
scattering coefficients
chutes
Glass
absorptivity

Keywords

  • blood charring
  • double integrating sphere
  • inverse adding doubling analysis
  • optical coefficient

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Radiology Nuclear Medicine and imaging

Cite this

Takahashi, M., Ito, A., & Arai, T. (2012). Optical property change of blood on an optical window boundary by 660-nm band laser irradiation. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE (Vol. 8221). [822116] https://doi.org/10.1117/12.905845

Optical property change of blood on an optical window boundary by 660-nm band laser irradiation. / Takahashi, Mei; Ito, Arisa; Arai, Tsunenori.

Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8221 2012. 822116.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Takahashi, M, Ito, A & Arai, T 2012, Optical property change of blood on an optical window boundary by 660-nm band laser irradiation. in Progress in Biomedical Optics and Imaging - Proceedings of SPIE. vol. 8221, 822116, Optical Interactions with Tissue and Cells XXIII, San Francisco, CA, United States, 12/1/23. https://doi.org/10.1117/12.905845
Takahashi M, Ito A, Arai T. Optical property change of blood on an optical window boundary by 660-nm band laser irradiation. In Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8221. 2012. 822116 https://doi.org/10.1117/12.905845
Takahashi, Mei ; Ito, Arisa ; Arai, Tsunenori. / Optical property change of blood on an optical window boundary by 660-nm band laser irradiation. Progress in Biomedical Optics and Imaging - Proceedings of SPIE. Vol. 8221 2012.
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