Origins of substance P- and calcitonin gene-related peptide-containing nerves in the internal carotid artery of rat

Jan Erik Hardebo, Norihiro Suzuki, Christer Owman

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

An aggregation of substance P (SP)- and calcitonin gene-related peptide (CGRP)-containing nerve cells (internal carotid mini-ganglion) is described at the junction between the greater superficial petrosal nerve and the internal carotid nerve close to the internal carotid artery. A retrograde tracer dye technique demonstrates that this ganglion and the trigeminal and superior vagal ganglia supply the internal carotid artery with SP/CGRP fibers at, above and below this level, respectively. Implications of this finding for cranial painful syndromes in man are discussed.

Original languageEnglish
Pages (from-to)39-45
Number of pages7
JournalNeuroscience Letters
Volume101
Issue number1
DOIs
Publication statusPublished - 1989 Jun 5

Keywords

  • Calcitonin gene-related peptide
  • Immunohistochemistry
  • Peptide
  • Sensory ganglia
  • Sensory nerve fiber
  • Substance P

ASJC Scopus subject areas

  • Neuroscience(all)

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