Oryzamutaic acids H-J, new alkaloids from an Oryza sativa mutant with yellow endosperm

Hiroshi Nakano, Seiji Kosemura, Mitsuru Yoshida, Rika Iwaura, Toshisada Suzuki, Ryota Kaji, Makoto Sakai

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2 Citations (Scopus)


Three new nitrogen-containing heterocyclic alkaloids, oryzamutaic acids H-J (1-3), were isolated from the endosperm (polished rice) of an Oryza sativa mutant. The structures and relative stereochemistries of 1-3 were elucidated on the basis of spectroscopic analyses. The presence of three carbons, each bound to a carboxyl group and a nitrogen atom in the structure of 1, suggests that oryzamutaic acids H-J (1-3) are generated from three molecules of a single amino acid.

Original languageEnglish
Pages (from-to)4953-4956
Number of pages4
JournalTetrahedron Letters
Issue number38
Publication statusPublished - 2010



  • Alkaloid
  • Oryza sativa
  • Oryzamutaic acids H-J
  • Poaceae

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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