Osteoporosis is less frequent in endometrial cancer survivors with hypertriglyceridemia

Akira Hirasawa, Kazuya Makita, Tomoko Akahane, Wataru Yamagami, Takeshi Makabe, Megumi Yokota, Yuko Horiba, Mariko Ogawa, Shigehisa Yanamoto, Rhota Deshimaru, Eiichirou Tominaga, Kouji Banno, Nobuyuki Susumu, Daisuke Aoki

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

We previously reported an association between dyslipidemia and endometrial cancers. Osteoporosis is also reported to relate with some cancers. A common etiologic event has been proposed between dyslipidemia and osteoporosis. However, the pattern of interrelationships among dyslipidemia, osteoporosis and endometrial cancer is not well understood. To improve the quality of life of endometrial cancer survivors, these relationships should be determined. This study included 179 Japanese menopausal women who underwent bilateral salpingo-oophorectomy, including 114 women with incident endometrial cancer and 65 without endometrial cancer. The women were categorized according to dyslipidemia status. Bone mineral density was measured and compared between groups. Osteoporosis was statistically more frequent in women with hypertriglyceridemia who did not have endometrial cancer. In contrast, osteoporosis was statistically less frequent in women with hypertriglyceridemia who had endometrial cancer. In this cross-sectional study in a Japanese population, osteoporosis was associated with hypertriglyceridemia in post-menopausal women without endometrial cancer, but was less frequent in endometrial cancer survivors with hypertriglyceridemia.

Original languageEnglish
Article numberhyu164
Pages (from-to)127-131
Number of pages5
JournalJapanese Journal of Clinical Oncology
Volume45
Issue number1
DOIs
Publication statusPublished - 2015 Jan 1

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Hypertriglyceridemia
Endometrial Neoplasms
Osteoporosis
Survivors
Dyslipidemias
Ovariectomy
Bone Density
Cross-Sectional Studies
Quality of Life

Keywords

  • Cancer survivor
  • Dyslipidemia
  • Endometrial cancer
  • Hypertriglyceridemia
  • Osteoporosis
  • Quality of life

ASJC Scopus subject areas

  • Oncology
  • Cancer Research
  • Radiology Nuclear Medicine and imaging
  • Medicine(all)

Cite this

Osteoporosis is less frequent in endometrial cancer survivors with hypertriglyceridemia. / Hirasawa, Akira; Makita, Kazuya; Akahane, Tomoko; Yamagami, Wataru; Makabe, Takeshi; Yokota, Megumi; Horiba, Yuko; Ogawa, Mariko; Yanamoto, Shigehisa; Deshimaru, Rhota; Tominaga, Eiichirou; Banno, Kouji; Susumu, Nobuyuki; Aoki, Daisuke.

In: Japanese Journal of Clinical Oncology, Vol. 45, No. 1, hyu164, 01.01.2015, p. 127-131.

Research output: Contribution to journalArticle

Hirasawa, A, Makita, K, Akahane, T, Yamagami, W, Makabe, T, Yokota, M, Horiba, Y, Ogawa, M, Yanamoto, S, Deshimaru, R, Tominaga, E, Banno, K, Susumu, N & Aoki, D 2015, 'Osteoporosis is less frequent in endometrial cancer survivors with hypertriglyceridemia', Japanese Journal of Clinical Oncology, vol. 45, no. 1, hyu164, pp. 127-131. https://doi.org/10.1093/jjco/hyu164
Hirasawa, Akira ; Makita, Kazuya ; Akahane, Tomoko ; Yamagami, Wataru ; Makabe, Takeshi ; Yokota, Megumi ; Horiba, Yuko ; Ogawa, Mariko ; Yanamoto, Shigehisa ; Deshimaru, Rhota ; Tominaga, Eiichirou ; Banno, Kouji ; Susumu, Nobuyuki ; Aoki, Daisuke. / Osteoporosis is less frequent in endometrial cancer survivors with hypertriglyceridemia. In: Japanese Journal of Clinical Oncology. 2015 ; Vol. 45, No. 1. pp. 127-131.
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