Outcomes of percutaneous coronary intervention performed with or without preprocedural dual antiplatelet therapy

Yukinori Ikegami; Shun Kohsaka; Hiroaki Miyata; Ikuko Ueda; Jun Fuse; Munehisa Sakamoto; Yasuyuki Shiraishi; Yohei Numasawa; Koji Negishi; Iwao Nakamura; Yuichiro Maekawa; Yukihiko Momiyama; Keiichi Fukuda

doi:10.1253/circj.CJ-15-0484

Outcomes of percutaneous coronary intervention performed with or without preprocedural dual antiplatelet therapy

Yukinori Ikegami, Shun Kohsaka, Hiroaki Miyata, Ikuko Ueda, Jun Fuse, Munehisa Sakamoto, Yasuyuki Shiraishi, Yohei Numasawa, Koji Negishi, Iwao Nakamura, Yuichiro Maekawa, Yukihiko Momiyama, Keiichi Fukuda

Research output: Contribution to journal › Article

8 Citations (Scopus)

Abstract

Background:Preprocedural dual antiplatelet therapy (DAPT) in percutaneous coronary interventions (PCI) has been shown to improve outcomes; however, the efficacy of the procedure and its complications in Japanese patients remain largely unexplored, so we examined the risks and benefits of DAPT before PCI and its association with in-hospital outcomes.Methods and Results:We analyzed data from patients who had undergone PCI at 12 centers within the metropolitan Tokyo area between September 2008 and September 2013.Our study group comprised 6,528 patients, of whom 2,079 (31.8%) were not administered preprocedural DAPT. Non-use of preprocedural DAPT was associated with death, postprocedural shock, or heart failure (odds ratio [OR]: 1.47, 95% confidence interval [CI]: 1.10–1.96, P=0.009), and postprocedural myocardial infarction (OR: 1.41, 95% CI: 1.18–1.69, P

Original language	English
Pages (from-to)	2598-2607
Number of pages	10
Journal	Circulation Journal
Volume	79
Issue number	12
DOIs	https://doi.org/10.1253/circj.CJ-15-0484
Publication status	Published - 2015 Nov 25

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Keywords

Bleeding
Dual antiplatelet therapy
Japanese
Percutaneous coronary intervention

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

Cite this

Ikegami, Y., Kohsaka, S., Miyata, H., Ueda, I., Fuse, J., Sakamoto, M., Shiraishi, Y., Numasawa, Y., Negishi, K., Nakamura, I., Maekawa, Y., Momiyama, Y., & Fukuda, K. (2015). Outcomes of percutaneous coronary intervention performed with or without preprocedural dual antiplatelet therapy. Circulation Journal, 79(12), 2598-2607. https://doi.org/10.1253/circj.CJ-15-0484

Outcomes of percutaneous coronary intervention performed with or without preprocedural dual antiplatelet therapy. / Ikegami, Yukinori; Kohsaka, Shun ; Miyata, Hiroaki; Ueda, Ikuko; Fuse, Jun; Sakamoto, Munehisa; Shiraishi, Yasuyuki; Numasawa, Yohei; Negishi, Koji; Nakamura, Iwao; Maekawa, Yuichiro; Momiyama, Yukihiko; Fukuda, Keiichi.

In: Circulation Journal, Vol. 79, No. 12, 25.11.2015, p. 2598-2607.

Research output: Contribution to journal › Article

Ikegami, Yukinori ; Kohsaka, Shun ; Miyata, Hiroaki ; Ueda, Ikuko ; Fuse, Jun ; Sakamoto, Munehisa ; Shiraishi, Yasuyuki ; Numasawa, Yohei ; Negishi, Koji ; Nakamura, Iwao ; Maekawa, Yuichiro ; Momiyama, Yukihiko ; Fukuda, Keiichi. / Outcomes of percutaneous coronary intervention performed with or without preprocedural dual antiplatelet therapy. In: Circulation Journal. 2015 ; Vol. 79, No. 12. pp. 2598-2607.

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