Outpatient chemotherapy with oral UFT (tegafur and uracil) and cisplatin against metastatic non-small cell lung carcinoma--an effective case

T. Uehara, T. Yano, T. Kanematsu, Y. Terazaki, S. Kuninaka, Y. Fukuyama, H. Yokoyama, H. Asoh, Y. Ichinose

Research output: Contribution to journalArticle

Abstract

A 64-year-old man underwent a left pneumonectomy for squamous cell carcinoma of the left lung in July 1995. In May 1996, right pelvic bone metastasis occurred and was well controlled by the concurrent chemoradiotherapy; UFT (600 mg/body, day 1-14) and cisplatin (80 mg/m2, day 8) with a total 50.4 Gy of irradiation. In August 1996, left renal metastasis occurred, but regressed after two cycles of combination chemotherapy with UFT and cisplatin. In January 1997, multiple lung metastasis occurred. In accordance with the patient's request, combination chemotherapy was performed at the outpatient clinic. UFT (250 mg/m2) was given orally every day while cisplatin (60-80 mg/m2), fractionated in 3 or 5 days, was intravenously administered at an interval of 4 weeks or longer. The patient has continued the treatment for one year without serious (G3, 4) adverse events. During the treatment, the tumor growth was slow with a repeated cycle of progression and regression. The outpatient chemotherapy using UFT and cisplatin is considered to be useful, especially for the better quality of life of patients.

Original languageEnglish
Pages (from-to)137-139
Number of pages3
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume26
Issue number1
Publication statusPublished - 1999 Jan
Externally publishedYes

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Tegafur
Uracil
Non-Small Cell Lung Carcinoma
Cisplatin
Outpatients
Drug Therapy
Neoplasm Metastasis
Combination Drug Therapy
Pelvic Bones
Lung
Pneumonectomy
Chemoradiotherapy
Ambulatory Care Facilities
Squamous Cell Carcinoma
Quality of Life
Kidney
Therapeutics
Growth
Neoplasms

ASJC Scopus subject areas

  • Cancer Research
  • Pharmacology

Cite this

Uehara, T., Yano, T., Kanematsu, T., Terazaki, Y., Kuninaka, S., Fukuyama, Y., ... Ichinose, Y. (1999). Outpatient chemotherapy with oral UFT (tegafur and uracil) and cisplatin against metastatic non-small cell lung carcinoma--an effective case. Gan to kagaku ryoho. Cancer & chemotherapy, 26(1), 137-139.

Outpatient chemotherapy with oral UFT (tegafur and uracil) and cisplatin against metastatic non-small cell lung carcinoma--an effective case. / Uehara, T.; Yano, T.; Kanematsu, T.; Terazaki, Y.; Kuninaka, S.; Fukuyama, Y.; Yokoyama, H.; Asoh, H.; Ichinose, Y.

In: Gan to kagaku ryoho. Cancer & chemotherapy, Vol. 26, No. 1, 01.1999, p. 137-139.

Research output: Contribution to journalArticle

Uehara, T, Yano, T, Kanematsu, T, Terazaki, Y, Kuninaka, S, Fukuyama, Y, Yokoyama, H, Asoh, H & Ichinose, Y 1999, 'Outpatient chemotherapy with oral UFT (tegafur and uracil) and cisplatin against metastatic non-small cell lung carcinoma--an effective case', Gan to kagaku ryoho. Cancer & chemotherapy, vol. 26, no. 1, pp. 137-139.
Uehara, T. ; Yano, T. ; Kanematsu, T. ; Terazaki, Y. ; Kuninaka, S. ; Fukuyama, Y. ; Yokoyama, H. ; Asoh, H. ; Ichinose, Y. / Outpatient chemotherapy with oral UFT (tegafur and uracil) and cisplatin against metastatic non-small cell lung carcinoma--an effective case. In: Gan to kagaku ryoho. Cancer & chemotherapy. 1999 ; Vol. 26, No. 1. pp. 137-139.
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