Abstract
The Pd-peroxo complex (dioxygen)bis(triphenyIphosphine)palladium [Pd(Ph3P)202] caused epoxidation of olefins and oxidations of sulfides and sulfoxides in the presence of carboxylic acid derivatives. The Co-superoxo complex cobalt bis(salicylaldehyde)-3,3/ -diamino-di-n-propylamine [Co(Salpr)02] also oxidized sulfides to sulfoxides during the reaction with carboxylic acid derivatives. These oxidations were dependent upon the presence of a metal-dioxygen complex and an electrophile such as acyl cation. Metal-acylperoxide, generated in situ by the reaction of metal-dioxygen complex with a carboxylic acid derivative, could promote heterolytic cleavage of the 0–0 bond of dioxygen coordinated to metal to form a metal-oxo complex, which seems to be the ultimate species mediating the oxidations.
Original language | English |
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Pages (from-to) | 1997-2002 |
Number of pages | 6 |
Journal | Chemical and Pharmaceutical Bulletin |
Volume | 36 |
Issue number | 6 |
DOIs | |
Publication status | Published - 1988 Jan 1 |
Externally published | Yes |
Keywords
- (dioxygen)bis(triphenylphosphine)palladium S-oxidation epoxidation cobalt bis(salicylaldehyde)-3
- 3'diamino-di-n-propylamine metal-oxo oxene transfer
ASJC Scopus subject areas
- Chemistry(all)
- Drug Discovery