Oxidative cyclization of isodityrosine tripeptides: optimized condition and application of electrochemically generated thallium(III) ion

Takamasa Tanabe, Rika Obata, Shigeru Nishiyama

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3 Citations (Scopus)

Abstract

Thallium(III) trinitrate oxidation of the tripeptide, which was a synthetic precursor of the 17-membered isodityrosine natural product, eurypamide, was investigated to give the desired cyclized compound in 96% yield at best. In addition, the thallium(III) species generated by electrochemical oxidation of thallium(I) successfully produced the target compounds.

Original languageEnglish
Pages (from-to)113-118
Number of pages6
JournalHeterocycles
Volume69
Issue number1
Publication statusPublished - 2006 Dec 1

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ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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