Oxidative deprotection of 1,3-dithiane group using NaClO2 and NaH2PO4 in aqueous methanol

Takahiro Ichige, Annu Miyake, Naoki Kanoh, Masaya Nakata

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

The 1,3-dithiane group was oxidatively deprotected under the conditions of sodium chlorite, sodium dihydrogenphosphate, and 2-methyl-2-butene in 3:1 methanol-water at room temperature in good yield.

Original languageEnglish
Pages (from-to)1686-1690
Number of pages5
JournalSynlett
Issue number10
DOIs
Publication statusPublished - 2004 Aug 9

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Keywords

  • Deprotection
  • Protecting groups
  • Sodium chlorite
  • Sodium dihydrogenphosphate
  • Thioacetals

ASJC Scopus subject areas

  • Organic Chemistry

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