TY - GEN
T1 - Pairing single adherent cells in the dynamic microarray
AU - Teshima, T.
AU - Onoe, H.
AU - Kuribayashi-Shigetomi, K.
AU - Takeuchi, S.
PY - 2011/4/13
Y1 - 2011/4/13
N2 - This paper describes a dynamic microarray system for pairing adherent cells at single cell level. By introducing single cells cultured on mobile Parylene microplates into the system, we achieved pairing of single cells maintaining their physiological properties. By taking advantage of processibility of Parylene, we changed the shape and fabricated microgrooves on the plate surface. These modifications enabled us to control cell stretch and morphology on the micro-sized plates and bring single cells into contact easily. We expect this method is applicable to the analysis of a variety of cell-cell communication between two single adherent cells.
AB - This paper describes a dynamic microarray system for pairing adherent cells at single cell level. By introducing single cells cultured on mobile Parylene microplates into the system, we achieved pairing of single cells maintaining their physiological properties. By taking advantage of processibility of Parylene, we changed the shape and fabricated microgrooves on the plate surface. These modifications enabled us to control cell stretch and morphology on the micro-sized plates and bring single cells into contact easily. We expect this method is applicable to the analysis of a variety of cell-cell communication between two single adherent cells.
UR - http://www.scopus.com/inward/record.url?scp=79953803314&partnerID=8YFLogxK
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U2 - 10.1109/MEMSYS.2011.5734364
DO - 10.1109/MEMSYS.2011.5734364
M3 - Conference contribution
AN - SCOPUS:79953803314
SN - 9781424496327
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 71
EP - 74
BT - 2011 IEEE 24th International Conference on Micro Electro Mechanical Systems, MEMS 2011
T2 - 24th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2011
Y2 - 23 January 2011 through 27 January 2011
ER -