Pairing single adherent cells in the dynamic microarray

T. Teshima, Hiroaki Onoe, K. Kuribayashi-Shigetomi, S. Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper describes a dynamic microarray system for pairing adherent cells at single cell level. By introducing single cells cultured on mobile Parylene microplates into the system, we achieved pairing of single cells maintaining their physiological properties. By taking advantage of processibility of Parylene, we changed the shape and fabricated microgrooves on the plate surface. These modifications enabled us to control cell stretch and morphology on the micro-sized plates and bring single cells into contact easily. We expect this method is applicable to the analysis of a variety of cell-cell communication between two single adherent cells.

Original languageEnglish
Title of host publicationProceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
Pages71-74
Number of pages4
DOIs
Publication statusPublished - 2011
Externally publishedYes
Event24th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2011 - Cancun, Mexico
Duration: 2011 Jan 232011 Jan 27

Other

Other24th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2011
CountryMexico
CityCancun
Period11/1/2311/1/27

Fingerprint

Microarrays
Communication
cells
parylene
cultured cells
communication

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Mechanical Engineering
  • Condensed Matter Physics
  • Electronic, Optical and Magnetic Materials

Cite this

Teshima, T., Onoe, H., Kuribayashi-Shigetomi, K., & Takeuchi, S. (2011). Pairing single adherent cells in the dynamic microarray. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS) (pp. 71-74). [5734364] https://doi.org/10.1109/MEMSYS.2011.5734364

Pairing single adherent cells in the dynamic microarray. / Teshima, T.; Onoe, Hiroaki; Kuribayashi-Shigetomi, K.; Takeuchi, S.

Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2011. p. 71-74 5734364.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Teshima, T, Onoe, H, Kuribayashi-Shigetomi, K & Takeuchi, S 2011, Pairing single adherent cells in the dynamic microarray. in Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)., 5734364, pp. 71-74, 24th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2011, Cancun, Mexico, 11/1/23. https://doi.org/10.1109/MEMSYS.2011.5734364
Teshima T, Onoe H, Kuribayashi-Shigetomi K, Takeuchi S. Pairing single adherent cells in the dynamic microarray. In Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2011. p. 71-74. 5734364 https://doi.org/10.1109/MEMSYS.2011.5734364
Teshima, T. ; Onoe, Hiroaki ; Kuribayashi-Shigetomi, K. ; Takeuchi, S. / Pairing single adherent cells in the dynamic microarray. Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS). 2011. pp. 71-74
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