Abstract
(Chemical Equation Presented) A new strategy for catalytic functionalization of C-H bonds by means of electrochemical oxidation is described. Combination of palladium-catalyzed aromatic C-H bond cleavage and halogenation with electrochemically generated halonium ions enables highly efficient, selective halogenations of aromatic compounds in a green-sustainable manner. The required reagents for this reaction are an arene and an aqueous hydrogen halide as substrates, a palladium salt as a catalyst, and an organic solvent. No further additives such as electrolytes, oxidants, or ligands are necessary to achieve effective catalytic activity. Several remarkable advantages of the use of the electrochemical method are also described.
| Original language | English |
|---|---|
| Pages (from-to) | 11310-11311 |
| Number of pages | 2 |
| Journal | Journal of the American Chemical Society |
| Volume | 131 |
| Issue number | 32 |
| DOIs | |
| Publication status | Published - 2009 Aug 19 |
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)
- Biochemistry
- Colloid and Surface Chemistry
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Kakiuchi, F., Kochi, T., Mutsutani, H., Kobayashi, N., Urano, S., Sato, M., Nishiyama, S., & Tanabe, T. (2009). Palladium-catalyzed aromatic C-H halogenation with hydrogen halides by means of electrochemical oxidation. Journal of the American Chemical Society, 131(32), 11310-11311. https://doi.org/10.1021/ja9049228