TY - JOUR
T1 - Palladium-catalyzed Aromatic C−H Functionalizations Utilizing Electrochemical Oxidations
AU - Kakiuchi, Fumitoshi
AU - Kochi, Takuya
N1 - Funding Information:
FK started transition‐metal‐catalyzed C−H functionalization using electrochemical reactions with Professor Shigeru Nishiyama and Dr. Takamasa Tanabe at Keio University in 2007, after moving to Keio University. They kindly taught us how to use the electrochemical equipments and run these experiments with many advices. We wish to express our sincere thanks to their collaboration. Since we started work on this research subject, many members of our group have contributed to the efforts. We wish to express our sincere appreciation to our co‐workers for their contributions. We also wish to acknowledge financial support, in part, by JST CREST Grant Number JPMJCR20R1.
Publisher Copyright:
© 2021 The Chemical Society of Japan & Wiley-VCH GmbH
PY - 2021
Y1 - 2021
N2 - Transition-metal-catalyzed electrochemical C−H functionalizations have been extensively studied as atom- and step-economical clean methods in organic synthesis. In this account, we described our efforts on the palladium-catalyzed electrochemical C−H functionalizations, including C−H halogenations of arylpyridines and benzamide derivatives using HCl/HBr and I2 as a halogen source, a one-pot process giving teraryls via the palladium-catalyzed electrochemical C−H iodination and subsequent Suzuki-Miyaura coupling, and an iodine-mediated oxidative homo-coupling reaction of arylpyridines.
AB - Transition-metal-catalyzed electrochemical C−H functionalizations have been extensively studied as atom- and step-economical clean methods in organic synthesis. In this account, we described our efforts on the palladium-catalyzed electrochemical C−H functionalizations, including C−H halogenations of arylpyridines and benzamide derivatives using HCl/HBr and I2 as a halogen source, a one-pot process giving teraryls via the palladium-catalyzed electrochemical C−H iodination and subsequent Suzuki-Miyaura coupling, and an iodine-mediated oxidative homo-coupling reaction of arylpyridines.
KW - C−H activation
KW - C−H halogenation
KW - electrochemical oxidation
KW - oxidative homocoupling
KW - palladium catalyst
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U2 - 10.1002/tcr.202100050
DO - 10.1002/tcr.202100050
M3 - Review article
AN - SCOPUS:85104062551
JO - Chemical record (New York, N.Y.)
JF - Chemical record (New York, N.Y.)
SN - 1527-8999
ER -