Palladium-catalyzed medium-ring formation for construction of the core structure of laurencia oxacycles: Synthetic study of laurendecumallene B

Yuji Yoshimitsu, Shinsuke Inuki, Shinya Oishi, Nobutaka Fujii, Hiroaki Ohno

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5 Citations (Scopus)


Palladium-catalyzed medium-ring formation from a cyclic propargyl carbonate via a ring-opening and -closing cascade proceeded at the central carbon atom of the propargyl unit to provide a tetrahydro-2H-oxocine derivative bearing the core structure of laurencia oxacycle. The synthetic application of this reaction to a possible laurendecumallene B precursor is also presented.

Original languageEnglish
Pages (from-to)3046-3049
Number of pages4
JournalOrganic Letters
Issue number12
Publication statusPublished - 2013 Jun 21


ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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