TY - JOUR
T1 - Papillary adenoma of the distal common bile duct
AU - Inagaki, Mitsuhiro
AU - Ishizaki, Akira
AU - Kino, Shuichi
AU - Onodera, Kazuhiko
AU - Matsumoto, Kakuya
AU - Yokoyama, Kazunori
AU - Makino, Isao
AU - Ojima, Hidenori
AU - Tokusashi, Yoshihiko
AU - Miyokawa, Naoyuki
AU - Kasai, Shinichi
PY - 1999/8/1
Y1 - 1999/8/1
N2 - A 73-year-old man with a papillary adenoma located in the distal common bile duct is reported. He underwent pylorus-preserving pancreatoduodenectomy. The lesion in the common bile duct featured papillary proliferation of the epithelium and fibrous elements with diffuse infiltration by inflammatory cells. Positive staining for MIB-1 (Ki-67) and p53 was identified in the nuclei of the proliferative epithelium. These findings suggested the malignant potential of this lesion. Further progress in imaging diagnostic techniques should increase the frequency with which such lesions are discovered. Even now, if mural irregularities and defects are found in the extrahepatic biliary system, especially the distal common bile duct, the possibility of such borderline biliary adenoma should be taken into consideration when making a diagnosis.
AB - A 73-year-old man with a papillary adenoma located in the distal common bile duct is reported. He underwent pylorus-preserving pancreatoduodenectomy. The lesion in the common bile duct featured papillary proliferation of the epithelium and fibrous elements with diffuse infiltration by inflammatory cells. Positive staining for MIB-1 (Ki-67) and p53 was identified in the nuclei of the proliferative epithelium. These findings suggested the malignant potential of this lesion. Further progress in imaging diagnostic techniques should increase the frequency with which such lesions are discovered. Even now, if mural irregularities and defects are found in the extrahepatic biliary system, especially the distal common bile duct, the possibility of such borderline biliary adenoma should be taken into consideration when making a diagnosis.
KW - MIB-1 (Ki-67 antigen)
KW - Papillary adenoma of the common bile duct
KW - Pylorus-preserving pancreatoduodenectomy
KW - p53
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U2 - 10.1007/s005350050310
DO - 10.1007/s005350050310
M3 - Article
C2 - 10452691
AN - SCOPUS:0032840238
SN - 0944-1174
VL - 34
SP - 535
EP - 539
JO - Journal of Gastroenterology
JF - Journal of Gastroenterology
IS - 4
ER -