TY - GEN
T1 - Parametric study for laser hot balloon angioplasty to suppress chronic restenosis
T2 - Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VI
AU - Arai, Tsunenori M.D.
AU - Miyake, Takayuki
AU - Sakurada, Masami
AU - Miyamoto, Akira M.D.
AU - Mizuno, Kyoichi M.D.
AU - Kikuchi, Makoto
AU - Nakamura, Haruo M.D.
AU - Utsumi, Atsushi
AU - Takeuchi, Kiyoshi
PY - 1996
Y1 - 1996
N2 - To suppress restenosis after the percutaneous transluminal coronary angioplasty (PTCA), we experimentally investigated the optimum parameter setting on the combination of the balloon temperature and heating duration of our laser hot balloon catheter in rabbit model. The rabbit femoral arteries were treated by our laser hot balloon of 2.5 mm in diameter with various balloon temperatures and durations at the range from 60 to 90 deg., and from 15 to 30 seconds, respectively. The histological examination showed that high temperature (greater than 70 deg.) was necessary to suppress hyperplasia of the vessel in chronic phase. The angiography of pre- and post-treatment and of 2 months after the treatment showed that high temperature with short heating duration (15-30 s) was the best setting for chronic patency of the treated vessels. The laser hot balloon angioplasty with the above mentioned parameter setting might realize significant improvement on chronic patency after PTCA.
AB - To suppress restenosis after the percutaneous transluminal coronary angioplasty (PTCA), we experimentally investigated the optimum parameter setting on the combination of the balloon temperature and heating duration of our laser hot balloon catheter in rabbit model. The rabbit femoral arteries were treated by our laser hot balloon of 2.5 mm in diameter with various balloon temperatures and durations at the range from 60 to 90 deg., and from 15 to 30 seconds, respectively. The histological examination showed that high temperature (greater than 70 deg.) was necessary to suppress hyperplasia of the vessel in chronic phase. The angiography of pre- and post-treatment and of 2 months after the treatment showed that high temperature with short heating duration (15-30 s) was the best setting for chronic patency of the treated vessels. The laser hot balloon angioplasty with the above mentioned parameter setting might realize significant improvement on chronic patency after PTCA.
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M3 - Conference contribution
AN - SCOPUS:0029748976
SN - 081942045X
SN - 9780819420459
T3 - Proceedings of SPIE - The International Society for Optical Engineering
SP - 36
EP - 39
BT - Proceedings of SPIE - The International Society for Optical Engineering
A2 - Anderson, R.Rox
Y2 - 27 January 1996 through 30 January 1996
ER -