Parametric study for laser hot balloon angioplasty to suppress chronic restenosis

animal experiment

Tsunenori Arai, Takayuki Miyake, Masami Sakurada, Akira M D Miyamoto, Kyoichi M D Mizuno, Makoto Kikuchi, Haruo M D Nakamura, Atsushi Utsumi, Kiyoshi Takeuchi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

12 Citations (Scopus)

Abstract

To suppress restenosis after the percutaneous transluminal coronary angioplasty (PTCA), we experimentally investigated the optimum parameter setting on the combination of the balloon temperature and heating duration of our laser hot balloon catheter in rabbit model. The rabbit femoral arteries were treated by our laser hot balloon of 2.5 mm in diameter with various balloon temperatures and durations at the range from 60 to 90 deg., and from 15 to 30 seconds, respectively. The histological examination showed that high temperature (greater than 70 deg.) was necessary to suppress hyperplasia of the vessel in chronic phase. The angiography of pre- and post-treatment and of 2 months after the treatment showed that high temperature with short heating duration (15-30 s) was the best setting for chronic patency of the treated vessels. The laser hot balloon angioplasty with the above mentioned parameter setting might realize significant improvement on chronic patency after PTCA.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsR.Rox Anderson
Pages36-39
Number of pages4
Volume2671
Publication statusPublished - 1996
Externally publishedYes
EventLasers in Surgery: Advanced Characterization, Therapeutics, and Systems VI - San Jose, CA, USA
Duration: 1996 Jan 271996 Jan 30

Other

OtherLasers in Surgery: Advanced Characterization, Therapeutics, and Systems VI
CitySan Jose, CA, USA
Period96/1/2796/1/30

Fingerprint

Balloons
Animals
Lasers
Experiments
Heating
Temperature
Angiography
Catheters

ASJC Scopus subject areas

  • Engineering(all)

Cite this

Arai, T., Miyake, T., Sakurada, M., Miyamoto, A. M. D., Mizuno, K. M. D., Kikuchi, M., ... Takeuchi, K. (1996). Parametric study for laser hot balloon angioplasty to suppress chronic restenosis: animal experiment. In R. R. Anderson (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (Vol. 2671, pp. 36-39)

Parametric study for laser hot balloon angioplasty to suppress chronic restenosis : animal experiment. / Arai, Tsunenori; Miyake, Takayuki; Sakurada, Masami; Miyamoto, Akira M D; Mizuno, Kyoichi M D; Kikuchi, Makoto; Nakamura, Haruo M D; Utsumi, Atsushi; Takeuchi, Kiyoshi.

Proceedings of SPIE - The International Society for Optical Engineering. ed. / R.Rox Anderson. Vol. 2671 1996. p. 36-39.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Arai, T, Miyake, T, Sakurada, M, Miyamoto, AMD, Mizuno, KMD, Kikuchi, M, Nakamura, HMD, Utsumi, A & Takeuchi, K 1996, Parametric study for laser hot balloon angioplasty to suppress chronic restenosis: animal experiment. in RR Anderson (ed.), Proceedings of SPIE - The International Society for Optical Engineering. vol. 2671, pp. 36-39, Lasers in Surgery: Advanced Characterization, Therapeutics, and Systems VI, San Jose, CA, USA, 96/1/27.
Arai T, Miyake T, Sakurada M, Miyamoto AMD, Mizuno KMD, Kikuchi M et al. Parametric study for laser hot balloon angioplasty to suppress chronic restenosis: animal experiment. In Anderson RR, editor, Proceedings of SPIE - The International Society for Optical Engineering. Vol. 2671. 1996. p. 36-39
Arai, Tsunenori ; Miyake, Takayuki ; Sakurada, Masami ; Miyamoto, Akira M D ; Mizuno, Kyoichi M D ; Kikuchi, Makoto ; Nakamura, Haruo M D ; Utsumi, Atsushi ; Takeuchi, Kiyoshi. / Parametric study for laser hot balloon angioplasty to suppress chronic restenosis : animal experiment. Proceedings of SPIE - The International Society for Optical Engineering. editor / R.Rox Anderson. Vol. 2671 1996. pp. 36-39
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