Path length correction for haemoglobin concentration measurement in exposed cortex by multi-spectral im aging

K. Sakaguchi, S. Furukawa, E. Okada, T. Katsura, A. Maki, H. Kawaguchi

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    Abstract

    The changes in the oxy-and deoxy-haemoglobins in the cortical tissue caused by brain functions have been measured by multi-spectral imaging of the exposed cortex. It is important for the accurate measurement of the concentration changes in the oxy-and deoxy-haemoglobins to consider the wavelength dependence of the mean optical path lengths of the detected light. In this study, the changes in the cerebral haemoglobin concentrations of guinea pigs are measured using a multi-spectral imaging system. The wavelength dependence of the optical path lengths is estimated from the multi-spectral im age of the exposed cortex in order to improve the haemoglobin concentration measurement.

    Original languageEnglish
    Title of host publicationBiomedical Topical Meeting, BIO 2006
    PublisherOptical Society of America
    ISBN (Print)1557528071, 9781557528070
    Publication statusPublished - 2006 Jan 1
    EventBiomedical Topical Meeting, BIO 2006 - Fort Lauderdale, FL, United States
    Duration: 2006 Mar 192006 Mar 19

    Publication series

    NameOptics InfoBase Conference Papers
    ISSN (Electronic)2162-2701

    Other

    OtherBiomedical Topical Meeting, BIO 2006
    CountryUnited States
    CityFort Lauderdale, FL
    Period06/3/1906/3/19

    ASJC Scopus subject areas

    • Instrumentation
    • Atomic and Molecular Physics, and Optics

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  • Cite this

    Sakaguchi, K., Furukawa, S., Okada, E., Katsura, T., Maki, A., & Kawaguchi, H. (2006). Path length correction for haemoglobin concentration measurement in exposed cortex by multi-spectral im aging. In Biomedical Topical Meeting, BIO 2006 (Optics InfoBase Conference Papers). Optical Society of America.