Pediatric myxopapillary ependymoma treated with subtotal resection and radiation therapy

A case report and review of the literature

H. Shirasawa, K. Ishii, A. Iwanami, Shuji Mikami, Y. Toyama, Morio Matsumoto, Masaya Nakamura

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Study design:Case report and review of the literature.Objectives: Myxopapillary ependymoma (MPE) is a relatively rare glioma that develops from the spinal part of the filum terminale, usually in adulthood. While it is generally benign, MPE can disseminate intraspinally, and this malignant behavior requires a multidisciplinary response with surgery and radiotherapy. We report here a case of MPE occurring in the lumbosacral spine area of an 8-year-old boy.Setting:Japan, Tokyo.Methods:We report here a case of MPE, treated with subtotal surgical resection followed by craniospinal irradiation (CSI), in an 8-year-old boy. The patient was referred to our hospital with a 6-month history of severe pain in the lower back and legs, paralysis of the legs and dysuria. Magnetic resonance imaging images showed a large tumor that filled the entire spinal canal below L1. After subtotal resection of the tumor, the pathological findings established a diagnosis of MPE. Since the tumor had perforated its capsule, increasing the risk of intraspinal dissemination, the patient underwent radiotherapy and CSI after surgery.Results:Magnetic resonance images obtained 3 years after the surgery did not show any recurrence of MPE.Conclusion:Although tumor resection followed by CSI can be considered an effective strategy for treating a child with MPE, long-term follow-up is necessary to ensure early detection of any local recurrence or dissemination of the tumor, or of post-radiotherapy scoliosis.

Original languageEnglish
JournalSpinal Cord
Volume52
Issue numberSUPPL. 2
DOIs
Publication statusPublished - 2014

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Ependymoma
Radiotherapy
Pediatrics
Craniospinal Irradiation
Neoplasms
Cauda Equina
Dysuria
Recurrence
Spinal Canal
Tokyo
Paraplegia
Scoliosis
Low Back Pain
Glioma
Capsules
Leg
Japan
Spine
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Medicine(all)

Cite this

Pediatric myxopapillary ependymoma treated with subtotal resection and radiation therapy : A case report and review of the literature. / Shirasawa, H.; Ishii, K.; Iwanami, A.; Mikami, Shuji; Toyama, Y.; Matsumoto, Morio; Nakamura, Masaya.

In: Spinal Cord, Vol. 52, No. SUPPL. 2, 2014.

Research output: Contribution to journalArticle

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