Pediatric myxopapillary ependymoma treated with subtotal resection and radiation therapy: A case report and review of the literature

H. Shirasawa, K. Ishii, A. Iwanami, S. Mikami, Y. Toyama, M. Matsumoto, M. Nakamura

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2 Citations (Scopus)

Abstract

Study design:Case report and review of the literature.Objectives: Myxopapillary ependymoma (MPE) is a relatively rare glioma that develops from the spinal part of the filum terminale, usually in adulthood. While it is generally benign, MPE can disseminate intraspinally, and this malignant behavior requires a multidisciplinary response with surgery and radiotherapy. We report here a case of MPE occurring in the lumbosacral spine area of an 8-year-old boy.Setting:Japan, Tokyo.Methods:We report here a case of MPE, treated with subtotal surgical resection followed by craniospinal irradiation (CSI), in an 8-year-old boy. The patient was referred to our hospital with a 6-month history of severe pain in the lower back and legs, paralysis of the legs and dysuria. Magnetic resonance imaging images showed a large tumor that filled the entire spinal canal below L1. After subtotal resection of the tumor, the pathological findings established a diagnosis of MPE. Since the tumor had perforated its capsule, increasing the risk of intraspinal dissemination, the patient underwent radiotherapy and CSI after surgery.Results:Magnetic resonance images obtained 3 years after the surgery did not show any recurrence of MPE.Conclusion:Although tumor resection followed by CSI can be considered an effective strategy for treating a child with MPE, long-term follow-up is necessary to ensure early detection of any local recurrence or dissemination of the tumor, or of post-radiotherapy scoliosis.

Original languageEnglish
Pages (from-to)S18-S20
JournalSpinal Cord
Volume52
Issue numberSUPPL. 2
DOIs
Publication statusPublished - 2014 Aug

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ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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