Pediatric oncologic emergencies: Clinical and imaging review for pediatricians

Atsuhiko Handa, Taiki Nozaki, Akari Makidono, Tetsuhiko Okabe, Yuka Morita, Kazutoshi Fujita, Masaki Matsusako, Tatsuo Kono, Yasuyuki Kurihara, Daisuke Hasegawa, Tadashi Kumamoto, Chitose Ogawa, Yuki Yuza, Atsushi Manabe

Research output: Contribution to journalReview articlepeer-review


Children with cancer are at increased risk of life-threatening emergencies, either from the cancer itself or related to the cancer treatment. These conditions need to be assessed and treated as early as possible to minimize morbidity and mortality. Cardiothoracic emergencies encompass a variety of pathologies, including pericardial effusion and cardiac tamponade, massive hemoptysis, superior vena cava syndrome, pulmonary embolism, and pneumonia. Abdominal emergencies include bowel obstruction, intussusception, perforation, tumor rupture, intestinal graft-versus-host disease, acute pancreatitis, neutropenic colitis, and obstructive uropathy. Radiology plays a vital role in the diagnosis of these emergencies. We here review the clinical features and imaging in pediatric patients with oncologic emergencies, including a review of recently published studies. Key radiological images are presented to highlight the radiological approach to diagnosis. Pediatricians, pediatric surgeons, and pediatric radiologists need to work together to arrive at the correct diagnosis and to ensure prompt and appropriate treatment strategies.

Original languageEnglish
Pages (from-to)122-139
Number of pages18
JournalPediatrics International
Issue number2
Publication statusPublished - 2019 Feb
Externally publishedYes


  • computed tomography
  • magnetic resonance
  • pediatric oncologic emergency
  • radiograph
  • ultrasound

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health


Dive into the research topics of 'Pediatric oncologic emergencies: Clinical and imaging review for pediatricians'. Together they form a unique fingerprint.

Cite this