Percutaneous cryoablation of small pulmonary malignant tumors under computed tomographic guidance with local anesthesia for nonsurgical candidates

Masafumi Kawamura, Yotaro Izumi, Norimasa Tsukada, Keisuke Asakura, Hiroaki Sugiura, Hideki Yashiro, Keiko Nakano, Seishi Nakatsuka, Sachio Kuribayashi, Koichi Kobayashi

Research output: Contribution to journalArticle

103 Citations (Scopus)

Abstract

Objective: Cryoablation of pulmonary metastases might be a useful therapy for nonsurgical candidates. Methods: The procedure was performed after achievement of local anesthesia for 35 tumors in 20 patients (12 male and 8 female patients; mean age, 57 years). The primary end point was the safety and feasibility of cryoablation, and the secondary end point was tumor control assessed by follow-up dynamic computed tomographic scanning performed every 3 months. Results: Of the 22 sessions of cryoablation, pneumothorax occurred in 11, hemoptysis occurred in 8, and there was 1 case of phrenic nerve palsy. The mean hospital stay was 2.6 days. There was local recurrence of 7 (20%) tumors in 7 (35%) patients during a 9- to 28-month (median, 21 months) follow-up period. One-year survival according to the Kaplan-Meier method was 89.4%. Conclusion: Percutaneous cryoablation therapy for metastatic lung tumors is feasible and minimally invasive, with satisfactory local control.

Original languageEnglish
Pages (from-to)1007-1013
Number of pages7
JournalJournal of Thoracic and Cardiovascular Surgery
Volume131
Issue number5
DOIs
Publication statusPublished - 2006 May 1

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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