Peripartum heart failure caused by left ventricular diastolic dysfunction

A case report

Jun Kakogawa, Takafumi Nako, Suguru Igarashi, Shin Nakamura, Mamoru Tanaka

Research output: Contribution to journalArticle

Abstract

Peripartum cardiomyopathy is a rare but potentially life-threatening condition. The current definition of peripartum cardiomyopathy only includes patients with systolic dysfunction. We describe a 25-year-old nulligravid patient with heart failure, i.e. left ventricular diastolic dysfunction with preserved systolic dysfunction during the third trimester of pregnancy. She complained of dyspnea and was referred to our hospital at 31 weeks of gestation. The patient met the clinical criteria for peripartum cardiomyopathy with the exception of systolic dysfunction. Brain-type natriuretic peptide levels peaked at 1447 pg/dL. The patient responded to therapy for heart failure and showed resolution of her diastolic dysfunction by 1 month postpartum. The case demonstrated the important role of diastolic dysfunction in peripartum heart failure and the possibility of clarifying the pathophysiology of peripartum cardiomyopathy by evaluating diastolic function. Further investigations are needed to provide evidence regarding the clinical role of diastolic dysfunction in peripartum heart failure.

Original languageEnglish
Pages (from-to)835-838
Number of pages4
JournalActa Obstetricia et Gynecologica Scandinavica
Volume93
Issue number8
DOIs
Publication statusPublished - 2014
Externally publishedYes

Fingerprint

Peripartum Period
Left Ventricular Dysfunction
Heart Failure
Cardiomyopathies
Brain Natriuretic Peptide
Third Pregnancy Trimester
Dyspnea
Postpartum Period
Pregnancy

Keywords

  • brain-type natriuretic peptide
  • diastolic dysfunction
  • peripartum cardiomyopathy
  • Peripartum heart failure
  • pregnancy

ASJC Scopus subject areas

  • Obstetrics and Gynaecology

Cite this

Peripartum heart failure caused by left ventricular diastolic dysfunction : A case report. / Kakogawa, Jun; Nako, Takafumi; Igarashi, Suguru; Nakamura, Shin; Tanaka, Mamoru.

In: Acta Obstetricia et Gynecologica Scandinavica, Vol. 93, No. 8, 2014, p. 835-838.

Research output: Contribution to journalArticle

Kakogawa, Jun ; Nako, Takafumi ; Igarashi, Suguru ; Nakamura, Shin ; Tanaka, Mamoru. / Peripartum heart failure caused by left ventricular diastolic dysfunction : A case report. In: Acta Obstetricia et Gynecologica Scandinavica. 2014 ; Vol. 93, No. 8. pp. 835-838.
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