Abstract
Background: To investigate the peripheral optical quality and its relationship with axial elongation, myopic progression in Japanese children. Methods: Twenty-nine Japanese children, ages 10 to 12 years old, with baseline refraction from +0.75D to -5.5 D, were included and followed for 9 months. The central and peripheral point spread functions (PSFs; 0, 10, 20, 30 nasally) were obtained at 0.25 D steps around ±2.5 D of best-focus PSF (BF-PSF) using double-pass PSF system. Modulation transfer function (MTF) area of the BF-PSF was calculated from BF-PSF to represent the peripheral optical quality. Relative peripheral defocus (RPD), the refraction of anterior/posterior focal lines, MTF area, and their correlations with myopia progression were analyzed. Results: The average refractive change in 9 months was -0.5 ± 0.8 D. The change in axial length was significantly positively correlated with the amount of myopic progression (P = 0.0058) and RPD (P = 0.0007, 0.0036 and 0.0040, at 10, 20, 30 respectively) at the initial visit, but did not correlate with the peripheral MTF area. Myopic progression of more than 0.5 D with axial elongation was observed in seven children (MP group). The RPDs at 20 and 30 in the MP group were significantly more hyperopic than in the non-MP group (P = 0.002 and 0.007), whereas there was no significant difference in axial length, and central and peripheral MTF area between the MP and non-MP groups. MP group had more hyperopic focal lines compared with non-MP group at 20 and 30. Conclusion: These results suggest that the progression of axial myopia in children is associated with hyperopic RPD and refraction of focal lines, not with peripheral optical quality.
| Original language | English |
|---|---|
| Pages (from-to) | 2451-2461 |
| Number of pages | 11 |
| Journal | Graefe's Archive for Clinical and Experimental Ophthalmology |
| Volume | 251 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2013 Oct |
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Keywords
- Keyword: Myopia progression
- Peripheral optical quality
- Peripheral refraction
- Point spread function
ASJC Scopus subject areas
- Ophthalmology
- Sensory Systems
- Cellular and Molecular Neuroscience
Cite this
Peripheral optical quality and myopia progression in children. / Yamaguchi, Takefumi; Ohnuma, Kazuhiko; Konomi, Kenji; Satake, Yoshiyuki; Shimazaki, Jun; Negishi, Kazuno.
In: Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 251, No. 10, 10.2013, p. 2451-2461.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Peripheral optical quality and myopia progression in children
AU - Yamaguchi, Takefumi
AU - Ohnuma, Kazuhiko
AU - Konomi, Kenji
AU - Satake, Yoshiyuki
AU - Shimazaki, Jun
AU - Negishi, Kazuno
PY - 2013/10
Y1 - 2013/10
N2 - Background: To investigate the peripheral optical quality and its relationship with axial elongation, myopic progression in Japanese children. Methods: Twenty-nine Japanese children, ages 10 to 12 years old, with baseline refraction from +0.75D to -5.5 D, were included and followed for 9 months. The central and peripheral point spread functions (PSFs; 0, 10, 20, 30 nasally) were obtained at 0.25 D steps around ±2.5 D of best-focus PSF (BF-PSF) using double-pass PSF system. Modulation transfer function (MTF) area of the BF-PSF was calculated from BF-PSF to represent the peripheral optical quality. Relative peripheral defocus (RPD), the refraction of anterior/posterior focal lines, MTF area, and their correlations with myopia progression were analyzed. Results: The average refractive change in 9 months was -0.5 ± 0.8 D. The change in axial length was significantly positively correlated with the amount of myopic progression (P = 0.0058) and RPD (P = 0.0007, 0.0036 and 0.0040, at 10, 20, 30 respectively) at the initial visit, but did not correlate with the peripheral MTF area. Myopic progression of more than 0.5 D with axial elongation was observed in seven children (MP group). The RPDs at 20 and 30 in the MP group were significantly more hyperopic than in the non-MP group (P = 0.002 and 0.007), whereas there was no significant difference in axial length, and central and peripheral MTF area between the MP and non-MP groups. MP group had more hyperopic focal lines compared with non-MP group at 20 and 30. Conclusion: These results suggest that the progression of axial myopia in children is associated with hyperopic RPD and refraction of focal lines, not with peripheral optical quality.
AB - Background: To investigate the peripheral optical quality and its relationship with axial elongation, myopic progression in Japanese children. Methods: Twenty-nine Japanese children, ages 10 to 12 years old, with baseline refraction from +0.75D to -5.5 D, were included and followed for 9 months. The central and peripheral point spread functions (PSFs; 0, 10, 20, 30 nasally) were obtained at 0.25 D steps around ±2.5 D of best-focus PSF (BF-PSF) using double-pass PSF system. Modulation transfer function (MTF) area of the BF-PSF was calculated from BF-PSF to represent the peripheral optical quality. Relative peripheral defocus (RPD), the refraction of anterior/posterior focal lines, MTF area, and their correlations with myopia progression were analyzed. Results: The average refractive change in 9 months was -0.5 ± 0.8 D. The change in axial length was significantly positively correlated with the amount of myopic progression (P = 0.0058) and RPD (P = 0.0007, 0.0036 and 0.0040, at 10, 20, 30 respectively) at the initial visit, but did not correlate with the peripheral MTF area. Myopic progression of more than 0.5 D with axial elongation was observed in seven children (MP group). The RPDs at 20 and 30 in the MP group were significantly more hyperopic than in the non-MP group (P = 0.002 and 0.007), whereas there was no significant difference in axial length, and central and peripheral MTF area between the MP and non-MP groups. MP group had more hyperopic focal lines compared with non-MP group at 20 and 30. Conclusion: These results suggest that the progression of axial myopia in children is associated with hyperopic RPD and refraction of focal lines, not with peripheral optical quality.
KW - Keyword: Myopia progression
KW - Peripheral optical quality
KW - Peripheral refraction
KW - Point spread function
UR - http://www.scopus.com/inward/record.url?scp=84890570272&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84890570272&partnerID=8YFLogxK
U2 - 10.1007/s00417-013-2398-0
DO - 10.1007/s00417-013-2398-0
M3 - Article
C2 - 23760671
AN - SCOPUS:84890570272
VL - 251
SP - 2451
EP - 2461
JO - Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie
JF - Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie
SN - 0065-6100
IS - 10
ER -