Peripheral optical quality and myopia progression in children

Takefumi Yamaguchi, Kazuhiko Ohnuma, Kenji Konomi, Yoshiyuki Satake, Jun Shimazaki, Kazuno Negishi

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Background: To investigate the peripheral optical quality and its relationship with axial elongation, myopic progression in Japanese children. Methods: Twenty-nine Japanese children, ages 10 to 12 years old, with baseline refraction from +0.75D to -5.5 D, were included and followed for 9 months. The central and peripheral point spread functions (PSFs; 0, 10, 20, 30 nasally) were obtained at 0.25 D steps around ±2.5 D of best-focus PSF (BF-PSF) using double-pass PSF system. Modulation transfer function (MTF) area of the BF-PSF was calculated from BF-PSF to represent the peripheral optical quality. Relative peripheral defocus (RPD), the refraction of anterior/posterior focal lines, MTF area, and their correlations with myopia progression were analyzed. Results: The average refractive change in 9 months was -0.5 ± 0.8 D. The change in axial length was significantly positively correlated with the amount of myopic progression (P = 0.0058) and RPD (P = 0.0007, 0.0036 and 0.0040, at 10, 20, 30 respectively) at the initial visit, but did not correlate with the peripheral MTF area. Myopic progression of more than 0.5 D with axial elongation was observed in seven children (MP group). The RPDs at 20 and 30 in the MP group were significantly more hyperopic than in the non-MP group (P = 0.002 and 0.007), whereas there was no significant difference in axial length, and central and peripheral MTF area between the MP and non-MP groups. MP group had more hyperopic focal lines compared with non-MP group at 20 and 30. Conclusion: These results suggest that the progression of axial myopia in children is associated with hyperopic RPD and refraction of focal lines, not with peripheral optical quality.

Original languageEnglish
Pages (from-to)2451-2461
Number of pages11
JournalGraefe's Archive for Clinical and Experimental Ophthalmology
Volume251
Issue number10
DOIs
Publication statusPublished - 2013 Oct

Fingerprint

Myopia

Keywords

  • Keyword: Myopia progression
  • Peripheral optical quality
  • Peripheral refraction
  • Point spread function

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

Cite this

Peripheral optical quality and myopia progression in children. / Yamaguchi, Takefumi; Ohnuma, Kazuhiko; Konomi, Kenji; Satake, Yoshiyuki; Shimazaki, Jun; Negishi, Kazuno.

In: Graefe's Archive for Clinical and Experimental Ophthalmology, Vol. 251, No. 10, 10.2013, p. 2451-2461.

Research output: Contribution to journalArticle

Yamaguchi, Takefumi ; Ohnuma, Kazuhiko ; Konomi, Kenji ; Satake, Yoshiyuki ; Shimazaki, Jun ; Negishi, Kazuno. / Peripheral optical quality and myopia progression in children. In: Graefe's Archive for Clinical and Experimental Ophthalmology. 2013 ; Vol. 251, No. 10. pp. 2451-2461.
@article{8236bd4425ff4ab38e26ac890865ad4e,
title = "Peripheral optical quality and myopia progression in children",
abstract = "Background: To investigate the peripheral optical quality and its relationship with axial elongation, myopic progression in Japanese children. Methods: Twenty-nine Japanese children, ages 10 to 12 years old, with baseline refraction from +0.75D to -5.5 D, were included and followed for 9 months. The central and peripheral point spread functions (PSFs; 0, 10, 20, 30 nasally) were obtained at 0.25 D steps around ±2.5 D of best-focus PSF (BF-PSF) using double-pass PSF system. Modulation transfer function (MTF) area of the BF-PSF was calculated from BF-PSF to represent the peripheral optical quality. Relative peripheral defocus (RPD), the refraction of anterior/posterior focal lines, MTF area, and their correlations with myopia progression were analyzed. Results: The average refractive change in 9 months was -0.5 ± 0.8 D. The change in axial length was significantly positively correlated with the amount of myopic progression (P = 0.0058) and RPD (P = 0.0007, 0.0036 and 0.0040, at 10, 20, 30 respectively) at the initial visit, but did not correlate with the peripheral MTF area. Myopic progression of more than 0.5 D with axial elongation was observed in seven children (MP group). The RPDs at 20 and 30 in the MP group were significantly more hyperopic than in the non-MP group (P = 0.002 and 0.007), whereas there was no significant difference in axial length, and central and peripheral MTF area between the MP and non-MP groups. MP group had more hyperopic focal lines compared with non-MP group at 20 and 30. Conclusion: These results suggest that the progression of axial myopia in children is associated with hyperopic RPD and refraction of focal lines, not with peripheral optical quality.",
keywords = "Keyword: Myopia progression, Peripheral optical quality, Peripheral refraction, Point spread function",
author = "Takefumi Yamaguchi and Kazuhiko Ohnuma and Kenji Konomi and Yoshiyuki Satake and Jun Shimazaki and Kazuno Negishi",
year = "2013",
month = "10",
doi = "10.1007/s00417-013-2398-0",
language = "English",
volume = "251",
pages = "2451--2461",
journal = "Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie",
issn = "0065-6100",
publisher = "Springer Verlag",
number = "10",

}

TY - JOUR

T1 - Peripheral optical quality and myopia progression in children

AU - Yamaguchi, Takefumi

AU - Ohnuma, Kazuhiko

AU - Konomi, Kenji

AU - Satake, Yoshiyuki

AU - Shimazaki, Jun

AU - Negishi, Kazuno

PY - 2013/10

Y1 - 2013/10

N2 - Background: To investigate the peripheral optical quality and its relationship with axial elongation, myopic progression in Japanese children. Methods: Twenty-nine Japanese children, ages 10 to 12 years old, with baseline refraction from +0.75D to -5.5 D, were included and followed for 9 months. The central and peripheral point spread functions (PSFs; 0, 10, 20, 30 nasally) were obtained at 0.25 D steps around ±2.5 D of best-focus PSF (BF-PSF) using double-pass PSF system. Modulation transfer function (MTF) area of the BF-PSF was calculated from BF-PSF to represent the peripheral optical quality. Relative peripheral defocus (RPD), the refraction of anterior/posterior focal lines, MTF area, and their correlations with myopia progression were analyzed. Results: The average refractive change in 9 months was -0.5 ± 0.8 D. The change in axial length was significantly positively correlated with the amount of myopic progression (P = 0.0058) and RPD (P = 0.0007, 0.0036 and 0.0040, at 10, 20, 30 respectively) at the initial visit, but did not correlate with the peripheral MTF area. Myopic progression of more than 0.5 D with axial elongation was observed in seven children (MP group). The RPDs at 20 and 30 in the MP group were significantly more hyperopic than in the non-MP group (P = 0.002 and 0.007), whereas there was no significant difference in axial length, and central and peripheral MTF area between the MP and non-MP groups. MP group had more hyperopic focal lines compared with non-MP group at 20 and 30. Conclusion: These results suggest that the progression of axial myopia in children is associated with hyperopic RPD and refraction of focal lines, not with peripheral optical quality.

AB - Background: To investigate the peripheral optical quality and its relationship with axial elongation, myopic progression in Japanese children. Methods: Twenty-nine Japanese children, ages 10 to 12 years old, with baseline refraction from +0.75D to -5.5 D, were included and followed for 9 months. The central and peripheral point spread functions (PSFs; 0, 10, 20, 30 nasally) were obtained at 0.25 D steps around ±2.5 D of best-focus PSF (BF-PSF) using double-pass PSF system. Modulation transfer function (MTF) area of the BF-PSF was calculated from BF-PSF to represent the peripheral optical quality. Relative peripheral defocus (RPD), the refraction of anterior/posterior focal lines, MTF area, and their correlations with myopia progression were analyzed. Results: The average refractive change in 9 months was -0.5 ± 0.8 D. The change in axial length was significantly positively correlated with the amount of myopic progression (P = 0.0058) and RPD (P = 0.0007, 0.0036 and 0.0040, at 10, 20, 30 respectively) at the initial visit, but did not correlate with the peripheral MTF area. Myopic progression of more than 0.5 D with axial elongation was observed in seven children (MP group). The RPDs at 20 and 30 in the MP group were significantly more hyperopic than in the non-MP group (P = 0.002 and 0.007), whereas there was no significant difference in axial length, and central and peripheral MTF area between the MP and non-MP groups. MP group had more hyperopic focal lines compared with non-MP group at 20 and 30. Conclusion: These results suggest that the progression of axial myopia in children is associated with hyperopic RPD and refraction of focal lines, not with peripheral optical quality.

KW - Keyword: Myopia progression

KW - Peripheral optical quality

KW - Peripheral refraction

KW - Point spread function

UR - http://www.scopus.com/inward/record.url?scp=84890570272&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84890570272&partnerID=8YFLogxK

U2 - 10.1007/s00417-013-2398-0

DO - 10.1007/s00417-013-2398-0

M3 - Article

C2 - 23760671

AN - SCOPUS:84890570272

VL - 251

SP - 2451

EP - 2461

JO - Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie

JF - Albrecht von Graefes Archiv für Klinische und Experimentelle Ophthalmologie

SN - 0065-6100

IS - 10

ER -