Abstract
The technique of epidermal cell culture developed by Green and colleagues made a breakthrough in the treatment of massive wounds in vivo with grown cells in vitro. In the past two decades, progress of culture methods and clinical practice have been made and now it is possible to treat extensive skin defect with large amounts of cultured epithelium. Since 1985, we have been successfully used cultured epidermis as autografts for the permanent coverage of full-thickness burn wounds or excised burn scars, giant nevi, tattoos and so on. Furthermore, cultured epidermis has been available as allografts to promote the healing of chronic skin ulcers or deep dermal burn. In this paper we describe our clinical experience of cultured epithelium grafting for the treatment of wounds and predict new trial of wound management and regeneration based on tissue engineering concept.
| Original language | English |
|---|---|
| Pages (from-to) | 118-128 |
| Number of pages | 11 |
| Journal | Human cell : official journal of Human Cell Research Society |
| Volume | 15 |
| Issue number | 3 |
| Publication status | Published - 2002 Sep |
| Externally published | Yes |
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ASJC Scopus subject areas
- Cell Biology
- Cancer Research
Cite this
Permanent restoration of human skin treated with cultured epithelium grafting--wound healing by stem cell based tissue engineering--. / Oshima, Hideo; Inoue, Hajime; Matsuzaki, Kyouichi; Tanabe, Masayoshi; Kumagai, Norio.
In: Human cell : official journal of Human Cell Research Society, Vol. 15, No. 3, 09.2002, p. 118-128.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Permanent restoration of human skin treated with cultured epithelium grafting--wound healing by stem cell based tissue engineering--.
AU - Oshima, Hideo
AU - Inoue, Hajime
AU - Matsuzaki, Kyouichi
AU - Tanabe, Masayoshi
AU - Kumagai, Norio
PY - 2002/9
Y1 - 2002/9
N2 - The technique of epidermal cell culture developed by Green and colleagues made a breakthrough in the treatment of massive wounds in vivo with grown cells in vitro. In the past two decades, progress of culture methods and clinical practice have been made and now it is possible to treat extensive skin defect with large amounts of cultured epithelium. Since 1985, we have been successfully used cultured epidermis as autografts for the permanent coverage of full-thickness burn wounds or excised burn scars, giant nevi, tattoos and so on. Furthermore, cultured epidermis has been available as allografts to promote the healing of chronic skin ulcers or deep dermal burn. In this paper we describe our clinical experience of cultured epithelium grafting for the treatment of wounds and predict new trial of wound management and regeneration based on tissue engineering concept.
AB - The technique of epidermal cell culture developed by Green and colleagues made a breakthrough in the treatment of massive wounds in vivo with grown cells in vitro. In the past two decades, progress of culture methods and clinical practice have been made and now it is possible to treat extensive skin defect with large amounts of cultured epithelium. Since 1985, we have been successfully used cultured epidermis as autografts for the permanent coverage of full-thickness burn wounds or excised burn scars, giant nevi, tattoos and so on. Furthermore, cultured epidermis has been available as allografts to promote the healing of chronic skin ulcers or deep dermal burn. In this paper we describe our clinical experience of cultured epithelium grafting for the treatment of wounds and predict new trial of wound management and regeneration based on tissue engineering concept.
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M3 - Article
VL - 15
SP - 118
EP - 128
JO - Human Cell
JF - Human Cell
SN - 0914-7470
IS - 3
ER -