Phakomatous choristoma of the eyelid: Immunohistochemical observation

Yoshio Kamada, Akihiko Sakata, Satoshi Nakadomari, Makoto Takehana

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

This article reports the first case of phakomatous choristoma of the eyelid in Japan. The tumor occurred in a 2-week-old boy and was located in the left lower lid near the inner canthus. An immunohistochemical study of this rare, congenital tumor was performed. The immunohistochemical analysis revealed that the epithelial cells of this tumor showed positive staining for vimentin, S-100 protein, and neuron-specific enolase, while they had no immunoreactivity for cytokeratin, glial fibrillary acidic protein, epithelial membrane antigen, or a macrophage marker. Both the epithelial cells and the central contents of the islands in this tumor showed positive staining with anti-human alpha crystallin monoclonal mouse IgG. These results strongly indicated that a phakomatous choristoma was of a lenticular origin.

Original languageEnglish
Pages (from-to)41-45
Number of pages5
JournalJapanese Journal of Ophthalmology
Volume42
Issue number1
DOIs
Publication statusPublished - 1998 Jan 1

Keywords

  • Congenital tumor
  • Crystallin
  • Eyelid
  • Phakomatous choristoma

ASJC Scopus subject areas

  • Ophthalmology

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