Abstract
This article reports the first case of phakomatous choristoma of the eyelid in Japan. The tumor occurred in a 2-week-old boy and was located in the left lower lid near the inner canthus. An immunohistochemical study of this rare, congenital tumor was performed. The immunohistochemical analysis revealed that the epithelial cells of this tumor showed positive staining for vimentin, S-100 protein, and neuron-specific enolase, while they had no immunoreactivity for cytokeratin, glial fibrillary acidic protein, epithelial membrane antigen, or a macrophage marker. Both the epithelial cells and the central contents of the islands in this tumor showed positive staining with anti-human alpha crystallin monoclonal mouse IgG. These results strongly indicated that a phakomatous choristoma was of a lenticular origin.
| Original language | English |
|---|---|
| Pages (from-to) | 41-45 |
| Number of pages | 5 |
| Journal | Japanese Journal of Ophthalmology |
| Volume | 42 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 1998 Jan |
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Keywords
- Congenital tumor
- Crystallin
- Eyelid
- Phakomatous choristoma
ASJC Scopus subject areas
- Ophthalmology
Cite this
Phakomatous choristoma of the eyelid : Immunohistochemical observation. / Kamada, Yoshio; Sakata, Akihiko; Nakadomari, Satoshi; Takehana, Makoto.
In: Japanese Journal of Ophthalmology, Vol. 42, No. 1, 01.1998, p. 41-45.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Phakomatous choristoma of the eyelid
T2 - Immunohistochemical observation
AU - Kamada, Yoshio
AU - Sakata, Akihiko
AU - Nakadomari, Satoshi
AU - Takehana, Makoto
PY - 1998/1
Y1 - 1998/1
N2 - This article reports the first case of phakomatous choristoma of the eyelid in Japan. The tumor occurred in a 2-week-old boy and was located in the left lower lid near the inner canthus. An immunohistochemical study of this rare, congenital tumor was performed. The immunohistochemical analysis revealed that the epithelial cells of this tumor showed positive staining for vimentin, S-100 protein, and neuron-specific enolase, while they had no immunoreactivity for cytokeratin, glial fibrillary acidic protein, epithelial membrane antigen, or a macrophage marker. Both the epithelial cells and the central contents of the islands in this tumor showed positive staining with anti-human alpha crystallin monoclonal mouse IgG. These results strongly indicated that a phakomatous choristoma was of a lenticular origin.
AB - This article reports the first case of phakomatous choristoma of the eyelid in Japan. The tumor occurred in a 2-week-old boy and was located in the left lower lid near the inner canthus. An immunohistochemical study of this rare, congenital tumor was performed. The immunohistochemical analysis revealed that the epithelial cells of this tumor showed positive staining for vimentin, S-100 protein, and neuron-specific enolase, while they had no immunoreactivity for cytokeratin, glial fibrillary acidic protein, epithelial membrane antigen, or a macrophage marker. Both the epithelial cells and the central contents of the islands in this tumor showed positive staining with anti-human alpha crystallin monoclonal mouse IgG. These results strongly indicated that a phakomatous choristoma was of a lenticular origin.
KW - Congenital tumor
KW - Crystallin
KW - Eyelid
KW - Phakomatous choristoma
UR - http://www.scopus.com/inward/record.url?scp=16744362021&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=16744362021&partnerID=8YFLogxK
U2 - 10.1016/S0021-5155(97)00101-9
DO - 10.1016/S0021-5155(97)00101-9
M3 - Article
C2 - 9507364
AN - SCOPUS:16744362021
VL - 42
SP - 41
EP - 45
JO - Japanese Journal of Ophthalmology
JF - Japanese Journal of Ophthalmology
SN - 0021-5155
IS - 1
ER -