Phosphoglyceride crystal deposition disease presenting as multiple paragastric masses

Shinichi Yachida, Noriyoshi Fukushima, Yukihiro Nakanishi, Satoshi Nimura, Masahiko Sato, Kazuaki Shimada, Katsutoshi Miura, Michiie Sakamoto

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Phosphoglycerides, also referred to as glycerophospholipids, are the major lipid component of all membranes. Phosphoglyceride crystal deposition disease (PCDD) is a new clinicopathological entity and, to our knowledge, only two cases have been reported previously (1, 2). The cause and underlying mechanisms remain unknown. While crystal deposition with gout (monosodium urate) and pseudogout (calcium pyrophosphate dihydrate) occurs mostly in and around the joints, phosphoglyceride crystals accumulate in soft tissues, particularly at sites of injury (1, 2). In this report, we describe a case of PCDD presenting as multiple paragastric masses after distal partial gastrectomy, making preoperative diagnosis difficult. We believe this is the first reported case of PCDD occurring at this site. Although PCDD is extremely rare, this condition should be considered in the differential diagnosis of abdominal masses in patients with a history of abdominal surgery.

Original languageEnglish
Pages (from-to)1413-1418
Number of pages6
JournalDigestive Diseases and Sciences
Volume47
Issue number6
DOIs
Publication statusPublished - 2002

Keywords

  • Crystal deposition
  • Epithelioid cell granuloma
  • Phosphoglyceride
  • Tumor-like mass

ASJC Scopus subject areas

  • Physiology
  • Gastroenterology

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    Yachida, S., Fukushima, N., Nakanishi, Y., Nimura, S., Sato, M., Shimada, K., Miura, K., & Sakamoto, M. (2002). Phosphoglyceride crystal deposition disease presenting as multiple paragastric masses. Digestive Diseases and Sciences, 47(6), 1413-1418. https://doi.org/10.1023/A:1015351320907