Photodegradation of lipopolysaccharides and the inhibition of macrophage activation by anthraquinone-boronic acid hybrids

Daisuke Takahashi; Takuya Miura; Kazunobu Toshima

doi:10.1039/c2cc33559j

Photodegradation of lipopolysaccharides and the inhibition of macrophage activation by anthraquinone-boronic acid hybrids

Daisuke Takahashi, Takuya Miura, Kazunobu Toshima

Department of Applied Chemistry

Research output: Contribution to journal › Article

8 Citations (Scopus)

Abstract

Target-selective photodegradation of 3-deoxy-d-manno-2-octulopyranosonic acid (KDO) was achieved without additives and under neutral conditions using a designed anthraquinone-boronic acid hybrid and long wavelength UV light irradiation. The hybrid can photodegrade lipopolysaccharides (LPS) and inhibit macrophage activation induced by LPS.

Original language	English
Pages (from-to)	7595-7597
Number of pages	3
Journal	Chemical Communications
Volume	48
Issue number	61
DOIs	https://doi.org/10.1039/c2cc33559j
Publication status	Published - 2012 Jul 4

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c2cc33559j

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Takahashi, D., Miura, T., & Toshima, K. (2012). Photodegradation of lipopolysaccharides and the inhibition of macrophage activation by anthraquinone-boronic acid hybrids. Chemical Communications, 48(61), 7595-7597. https://doi.org/10.1039/c2cc33559j

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abstract = "Target-selective photodegradation of 3-deoxy-d-manno-2-octulopyranosonic acid (KDO) was achieved without additives and under neutral conditions using a designed anthraquinone-boronic acid hybrid and long wavelength UV light irradiation. The hybrid can photodegrade lipopolysaccharides (LPS) and inhibit macrophage activation induced by LPS.",

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