Photodegradation of target oligosaccharides by light-activated small molecules

Daisuke Takahashi, Shingo Hirono, Chigusa Hayashi, Masayuki Igarashi, Yoshio Nishimura, Kazunobu Toshima

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Shine on, shine on: The designed anthraquinone/boronic acid hybrid 1 selectively caused the degradation of oligosaccharides that have a β-D-galactofuranoside residue, which is a unique component in mycobacterial cell walls. Degradation was achieved using long-wavelength UV radiation in the absence of any additives and under neutral conditions.

Original languageEnglish
Pages (from-to)10096-10100
Number of pages5
JournalAngewandte Chemie - International Edition
Volume49
Issue number52
DOIs
Publication statusPublished - 2010 Dec 27

Keywords

  • Mycobacterium tuberculosis
  • anthraquinones
  • boronic acids
  • carbohydrates
  • photochemistry

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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