Photodegradation of target oligosaccharides by light-activated small molecules

Daisuke Takahashi; Shingo Hirono; Chigusa Hayashi; Masayuki Igarashi; Yoshio Nishimura; Kazunobu Toshima

doi:10.1002/anie.201005161

Photodegradation of target oligosaccharides by light-activated small molecules

Daisuke Takahashi, Shingo Hirono, Chigusa Hayashi, Masayuki Igarashi, Yoshio Nishimura, Kazunobu Toshima

Department of Applied Chemistry

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

Shine on, shine on: The designed anthraquinone/boronic acid hybrid 1 selectively caused the degradation of oligosaccharides that have a β-D-galactofuranoside residue, which is a unique component in mycobacterial cell walls. Degradation was achieved using long-wavelength UV radiation in the absence of any additives and under neutral conditions.

Original language	English
Pages (from-to)	10096-10100
Number of pages	5
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	52
DOIs	https://doi.org/10.1002/anie.201005161
Publication status	Published - 2010 Dec 27

Keywords

Mycobacterium tuberculosis
anthraquinones
boronic acids
carbohydrates
photochemistry

ASJC Scopus subject areas

Catalysis
Chemistry(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1002/anie.201005161

Cite this

@article{ccfccfda8bf04c53a9a82ea5bc1e2337,

title = "Photodegradation of target oligosaccharides by light-activated small molecules",

abstract = "Shine on, shine on: The designed anthraquinone/boronic acid hybrid 1 selectively caused the degradation of oligosaccharides that have a β-D-galactofuranoside residue, which is a unique component in mycobacterial cell walls. Degradation was achieved using long-wavelength UV radiation in the absence of any additives and under neutral conditions.",

keywords = "Mycobacterium tuberculosis, anthraquinones, boronic acids, carbohydrates, photochemistry",

author = "Daisuke Takahashi and Shingo Hirono and Chigusa Hayashi and Masayuki Igarashi and Yoshio Nishimura and Kazunobu Toshima",

year = "2010",

month = dec,

day = "27",

doi = "10.1002/anie.201005161",

language = "English",

volume = "49",

pages = "10096--10100",

journal = "Angewandte Chemie - International Edition",

issn = "1433-7851",

publisher = "John Wiley and Sons Ltd",

number = "52",

}

TY - JOUR

T1 - Photodegradation of target oligosaccharides by light-activated small molecules

AU - Takahashi, Daisuke

AU - Hirono, Shingo

AU - Hayashi, Chigusa

AU - Igarashi, Masayuki

AU - Nishimura, Yoshio

AU - Toshima, Kazunobu

PY - 2010/12/27

Y1 - 2010/12/27

N2 - Shine on, shine on: The designed anthraquinone/boronic acid hybrid 1 selectively caused the degradation of oligosaccharides that have a β-D-galactofuranoside residue, which is a unique component in mycobacterial cell walls. Degradation was achieved using long-wavelength UV radiation in the absence of any additives and under neutral conditions.

AB - Shine on, shine on: The designed anthraquinone/boronic acid hybrid 1 selectively caused the degradation of oligosaccharides that have a β-D-galactofuranoside residue, which is a unique component in mycobacterial cell walls. Degradation was achieved using long-wavelength UV radiation in the absence of any additives and under neutral conditions.

KW - Mycobacterium tuberculosis

KW - anthraquinones

KW - boronic acids

KW - carbohydrates

KW - photochemistry

UR - http://www.scopus.com/inward/record.url?scp=78650473656&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=78650473656&partnerID=8YFLogxK

U2 - 10.1002/anie.201005161

DO - 10.1002/anie.201005161

M3 - Article

C2 - 21110364

AN - SCOPUS:78650473656

SN - 1433-7851

VL - 49

SP - 10096

EP - 10100

JO - Angewandte Chemie - International Edition

JF - Angewandte Chemie - International Edition

IS - 52

ER -

Photodegradation of target oligosaccharides by light-activated small molecules

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this