Physical activity in patients with gastrointestinal cancer undergoing outpatient chemotherapy

Megumi Iwakoshi, Tetsuya Tsuji, Hiromasa Takaishi, Yasuo Hamamoto, Tsunehiro Takahashi, Takashi Endo, Yuukou Kitagawa, Meigen Liu

Research output: Contribution to journalArticle

Abstract

Purpose: To determine factors affecting physical activity in outpatients with gastrointestinal cancer. Methods: This observational study applied the International Physical Activity Questionnaire (IPAQ) to identify factors affecting physical activity in outpatients (male, n=51; female, n=24; mean age, 64.2±10.2 years) with gastrointestinal cancer undergoing chemotherapy. Relationships between the main outcome measures, total weekly physical activity score (TPA) and total weekly energy expenditure (TEE), and patient background factors were analyzed. Results: The median duration of induction chemotherapy in the 75 outpatients who completed the IPAQ was 242.5 (range 7-2, 294) days. The TPA and TEE tended to decrease in older patients and were lower in all patients compared with age-specific standard values for healthy persons. Both values tended to increase to a greater extent among patients who worked than among those who did not, and being employed was significantly associated with Eastern Cooperative Oncology Group performance status (ECOG-PS). The TEE tended to be lower among patients with adverse events (AE) such as pain. Conclusion: Progressive cachexia, changes in lifestyle, and AE affected physical activity among outpatients with gastrointestinal cancer undergoing chemotherapy. Comprehensive support by an oncology team would probably play an important role in encouraging elderly patients to participate in physical activity.

Original languageEnglish
Pages (from-to)1367-1373
Number of pages7
JournalJapanese Journal of Cancer and Chemotherapy
Volume43
Issue number11
Publication statusPublished - 2016 Nov 1

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Gastrointestinal Neoplasms
Outpatients
Exercise
Drug Therapy
Energy Metabolism
Cachexia
Induction Chemotherapy
Observational Studies
Life Style
Outcome Assessment (Health Care)
Pain

Keywords

  • Anti-cancer drug
  • Cachexia
  • Physical fitness

ASJC Scopus subject areas

  • Medicine(all)
  • Oncology
  • Cancer Research

Cite this

Physical activity in patients with gastrointestinal cancer undergoing outpatient chemotherapy. / Iwakoshi, Megumi; Tsuji, Tetsuya; Takaishi, Hiromasa; Hamamoto, Yasuo; Takahashi, Tsunehiro; Endo, Takashi; Kitagawa, Yuukou; Liu, Meigen.

In: Japanese Journal of Cancer and Chemotherapy, Vol. 43, No. 11, 01.11.2016, p. 1367-1373.

Research output: Contribution to journalArticle

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