TY - JOUR
T1 - Pilot study on sentinel node biopsy in breast cancer
AU - Imoto, Shigeru
AU - Fukukita, Hiroyoshi
AU - Murakami, Kohji
AU - Ikeda, Hiroshi
AU - Moriyama, Noriyuki
PY - 2000
Y1 - 2000
N2 - Background and Objectives: Sentinel node biopsy (SNB) in breast cancer using indigo carmine was started in January 1998, and this method has proved feasible and reliable. From our initial experience, sentinel lymph nodes (SLNs) were identified in 65 of 88 cases of breast cancer (74%). Methods: Lymphatic mapping in breast cancer was assessed using radionuclide, technetium-99m human serum albumin or technetium-99m tin colloid. A pilot study on SNB with dye or a combined method was performed between August 1998 and January 1999. Results: SLNs were identified in 55 of 59 cases (93%). False-negative SLNs were found in 2 cases. The sensitivity and accuracy in all cases were 92% and 96%. SLNs in 52 cases were also diagnosed by immediate frozen sectioning. The sensitivity and accuracy were 89% and 96%. Conclusions: SNB in the combined method was the best way to identify SLNs in breast cancer. (C) 2000 Wiley-Liss, Inc.
AB - Background and Objectives: Sentinel node biopsy (SNB) in breast cancer using indigo carmine was started in January 1998, and this method has proved feasible and reliable. From our initial experience, sentinel lymph nodes (SLNs) were identified in 65 of 88 cases of breast cancer (74%). Methods: Lymphatic mapping in breast cancer was assessed using radionuclide, technetium-99m human serum albumin or technetium-99m tin colloid. A pilot study on SNB with dye or a combined method was performed between August 1998 and January 1999. Results: SLNs were identified in 55 of 59 cases (93%). False-negative SLNs were found in 2 cases. The sensitivity and accuracy in all cases were 92% and 96%. SLNs in 52 cases were also diagnosed by immediate frozen sectioning. The sensitivity and accuracy were 89% and 96%. Conclusions: SNB in the combined method was the best way to identify SLNs in breast cancer. (C) 2000 Wiley-Liss, Inc.
KW - Breast cancer
KW - Indigo carmine
KW - Lymphatic mapping
KW - Sentinel lymph nodes
KW - Sentinel node biopsy
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U2 - 10.1002/(SICI)1096-9098(200003)73:3<130::AID-JSO2>3.0.CO;2-X
DO - 10.1002/(SICI)1096-9098(200003)73:3<130::AID-JSO2>3.0.CO;2-X
M3 - Article
C2 - 10738263
AN - SCOPUS:0034104961
SN - 0022-4790
VL - 73
SP - 130
EP - 133
JO - Journal of Surgical Oncology
JF - Journal of Surgical Oncology
IS - 3
ER -
