Pinnamine, an alkaloidal marine toxin, isolated from Pinna muricata

N. Takada, M. Iwatsuki, Kiyotake Suenaga, D. Uemura

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

Pinnamine, a novel marine alkaloid, was isolated from the Okinawan bivalve Pinna muricata. Pinnamine was determined to be an alkaloid containing a dihydropyrone ring by spectroscopic analysis. The relative stereostructure of pinnamine was determined by an analysis of coupling constants and NOE experiments; the absolute stereostructure was determined by an analysis of the circular dichroism spectrum. Pinnamine exhibited significant acute toxicity against mice. (C) 2000 Elsevier Science Ltd.

Original languageEnglish
Pages (from-to)6425-6428
Number of pages4
JournalTetrahedron Letters
Volume41
Issue number33
Publication statusPublished - 2000 Aug 12
Externally publishedYes

Fingerprint

Marine Toxins
Alkaloids
Spectroscopic analysis
Bivalvia
Circular Dichroism
Toxicity
pinnamine
Experiments

Keywords

  • Acute toxicity
  • Alkaloid
  • Dihydropyrone
  • Pinna muricata
  • Pinnamine
  • Structure determination

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry
  • Drug Discovery

Cite this

Takada, N., Iwatsuki, M., Suenaga, K., & Uemura, D. (2000). Pinnamine, an alkaloidal marine toxin, isolated from Pinna muricata. Tetrahedron Letters, 41(33), 6425-6428.

Pinnamine, an alkaloidal marine toxin, isolated from Pinna muricata. / Takada, N.; Iwatsuki, M.; Suenaga, Kiyotake; Uemura, D.

In: Tetrahedron Letters, Vol. 41, No. 33, 12.08.2000, p. 6425-6428.

Research output: Contribution to journalArticle

Takada, N, Iwatsuki, M, Suenaga, K & Uemura, D 2000, 'Pinnamine, an alkaloidal marine toxin, isolated from Pinna muricata', Tetrahedron Letters, vol. 41, no. 33, pp. 6425-6428.
Takada N, Iwatsuki M, Suenaga K, Uemura D. Pinnamine, an alkaloidal marine toxin, isolated from Pinna muricata. Tetrahedron Letters. 2000 Aug 12;41(33):6425-6428.
Takada, N. ; Iwatsuki, M. ; Suenaga, Kiyotake ; Uemura, D. / Pinnamine, an alkaloidal marine toxin, isolated from Pinna muricata. In: Tetrahedron Letters. 2000 ; Vol. 41, No. 33. pp. 6425-6428.
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