TY - JOUR
T1 - Pinnatoxins B and C, the most toxic components in the pinnatoxin series from the Okinawan bivalve Pinna muricata
AU - Takada, Noboru
AU - Umemura, Naoyoshi
AU - Suenaga, Kiyotake
AU - Chou, Tong
AU - Nagatsu, Akito
AU - Haino, Takeharu
AU - Yamada, Kaoru
AU - Uemura, Daisuke
PY - 2001/5/14
Y1 - 2001/5/14
N2 - Pinnatoxins B and C, the most toxic components in the pinnatoxin series, were successfully purified from the Okinawan bivalve Pinna muricata. Their gross structures were determined based on NMR and MS/MS spectral analyses. Their stereostructures were mainly determined by transformation reactions. Pinnatoxins B and C, C-34 epimers of each other, have an amphoteric macrocycle composed of 6,7-spiro, 5,6-bicyclo and 6,5,6-trispiro ketal rings, the same as in pinnatoxins A and D.
AB - Pinnatoxins B and C, the most toxic components in the pinnatoxin series, were successfully purified from the Okinawan bivalve Pinna muricata. Their gross structures were determined based on NMR and MS/MS spectral analyses. Their stereostructures were mainly determined by transformation reactions. Pinnatoxins B and C, C-34 epimers of each other, have an amphoteric macrocycle composed of 6,7-spiro, 5,6-bicyclo and 6,5,6-trispiro ketal rings, the same as in pinnatoxins A and D.
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U2 - 10.1016/S0040-4039(01)00480-4
DO - 10.1016/S0040-4039(01)00480-4
M3 - Article
AN - SCOPUS:0035858744
VL - 42
SP - 3491
EP - 3494
JO - Tetrahedron Letters
JF - Tetrahedron Letters
SN - 0040-4039
IS - 20
ER -