Background: Chronic pulmonary thromboembolism (CPTE) leads to pulmonary arterial hypertension (PAH). The electrocardiography (ECG) of the patients with CPTE reflects the right-sided heart overload due to PAH. Recently, percutaneous transluminal pulmonary angioplasty (PTPA) has been demonstrated to be effective for some patients with CPTE. The purpose was to investigate the changes of ECG in patients underwent PTPA. Methods: We performed PTPA to 18 patients with CPTE. ECG was recorded before and after PTPA. Hemodynamic variables through right heart catheterization were determined at the same time. Results: The hemodynamics after PTPA was significantly improved compared to the baseline (mean pulmonary arterial pressure, 46.4 mmHg vs. 34.4 mmHg; pulmonary vascular resistance, 14.2 wood units vs. 7.8 wood units). The P amplitude in lead II was significantly decreased (2.7 mV vs. 2.0 mV). The electrical axis of QRS waves went leftward significantly (102.6° vs. 89.9°). The R/S in lead V5 was significantly increased (1.5 vs. 2.7). Conclusions: Our results suggest that the changes of ECG reflect properly the changes of right-sided heart overload by PTPA. The evaluation of ECG is a simple and easy method to assess the treatment efficacy of PTPA.
- chronic pulmonary thromboembolism
- percutaneous transluminal pulmonary angioplasty
- pulmonary arterial hypertension
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine