Plasma cell granuloma extending from the extracranial to the intracranial space associated with Epstein-Barr virus infection

Atsushi Fukunaga, Kazunari Yoshida, Mitsuhiro Otani, Yoshihiro Ogawa, Takashi Horiguchi, Masayuki Ishihara, Shigeo Toya, Takeshi Kawase

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

A 70-year-old male presented with a plasma cell granuloma extending from the extracranial to the intracranial space. Findings of preoperative magnetic resonance imaging and intraoperative observation indicated that the lesion extended from the temporal muscle to the subarachnoid space, penetrating the frontal bone. The subarachnoid lesion was composed of neutrophils indicating the presence of acute or subacute inflammation. The final diagnosis of the resected tumor was plasma cell granuloma. High levels of antibodies against Epstein-Barr (EB) virus in the cerebrospinal fluid and the immunohistochemical demonstration of EB nuclear antigens in the plasma cell granuloma suggested that EB virus infection was associated with the development of plasma cell granuloma in this patient.

Original languageEnglish
Pages (from-to)292-296
Number of pages5
JournalNeurologia medico-chirurgica
Volume38
Issue number5
Publication statusPublished - 1998 May 1

Keywords

  • Central nervous system
  • Epstein-Barr virus
  • Plasma cell granuloma
  • Skull

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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    Fukunaga, A., Yoshida, K., Otani, M., Ogawa, Y., Horiguchi, T., Ishihara, M., Toya, S., & Kawase, T. (1998). Plasma cell granuloma extending from the extracranial to the intracranial space associated with Epstein-Barr virus infection. Neurologia medico-chirurgica, 38(5), 292-296.