Plasma concentration of acetylcholine in young women

Koichiro Kawashima, Hisayo Oohata, Kazuko Fujimoto, Takeshi Suzuki

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

A sensitive and specific radioimmunoassay was applied to the determination of acetylcholine (ACh) in plasma. The concentration of ACh in plasma sampled from 32 young women was 456.1 ± 53.1 (mean ± S.E.M.) pg/ml. No significant correlations were observed between plasma concentration of ACh and acetylcholinesterase (AChE) activity, or gonadal hormones. These data demonstrate that an amount of ACh measurable by radioimmunoassay is present in plasma and plasma ACh is not regulated by AChE activity and the menstrual cycle in young women. The origin and physiological as well as pathophysiological significance of ACh in plasma remain to be clarified.

Original languageEnglish
Pages (from-to)339-342
Number of pages4
JournalNeuroscience Letters
Volume80
Issue number3
DOIs
Publication statusPublished - 1987 Oct 5

Keywords

  • Acetylcholinesterase
  • Gonadal hormone
  • Menstrual cycle
  • Plasma acetylcholine
  • Radioimmunoassay
  • Young woman

ASJC Scopus subject areas

  • Neuroscience(all)

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