Pneumonitis induced by ou-gon (scullcap)

Kei Takeshita, Yoshifumi Saisho, Kumi Kitamura, Noriko Kaburagi, Tomohiro Funabiki, Toshiyuki Inamura, Yoshitaka Oyamada, Koichiro Asano, Kazuhiro Yamaguchi

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

A 53-year-old Japanese man with recurrent interstitial pneumonia was referred to us. The patient had taken a traditional herb medicine, otsu-ji-to, before the onset of pneumonia. A provocation test for each herbal ingredient contained in otsu-ji-to revealed that the pneumonitis had been induced by ou-gon (scullcap). Lymphocytosis with the CD8+ T-cell subset predominance was found in the bronchoalveolar lavage fluid and lymphocytic alveolitis was noted in the transbronchial lung biopsy specimen after the provocation test. Ou-gon, or scullcap, should be included in the list of drugs with definite causal association with pneumonitis.

Original languageEnglish
Pages (from-to)764-768
Number of pages5
JournalInternal Medicine
Volume40
Issue number8
Publication statusPublished - 2001 Aug

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Pneumonia
Lymphocytosis
Interstitial Lung Diseases
Bronchoalveolar Lavage Fluid
T-Lymphocyte Subsets
Traditional Medicine
Biopsy
Lung
Pharmaceutical Preparations

Keywords

  • Drug-induced pneumonitis
  • Herb medicine

ASJC Scopus subject areas

  • Internal Medicine

Cite this

Takeshita, K., Saisho, Y., Kitamura, K., Kaburagi, N., Funabiki, T., Inamura, T., ... Yamaguchi, K. (2001). Pneumonitis induced by ou-gon (scullcap). Internal Medicine, 40(8), 764-768.

Pneumonitis induced by ou-gon (scullcap). / Takeshita, Kei; Saisho, Yoshifumi; Kitamura, Kumi; Kaburagi, Noriko; Funabiki, Tomohiro; Inamura, Toshiyuki; Oyamada, Yoshitaka; Asano, Koichiro; Yamaguchi, Kazuhiro.

In: Internal Medicine, Vol. 40, No. 8, 08.2001, p. 764-768.

Research output: Contribution to journalArticle

Takeshita, K, Saisho, Y, Kitamura, K, Kaburagi, N, Funabiki, T, Inamura, T, Oyamada, Y, Asano, K & Yamaguchi, K 2001, 'Pneumonitis induced by ou-gon (scullcap)', Internal Medicine, vol. 40, no. 8, pp. 764-768.
Takeshita K, Saisho Y, Kitamura K, Kaburagi N, Funabiki T, Inamura T et al. Pneumonitis induced by ou-gon (scullcap). Internal Medicine. 2001 Aug;40(8):764-768.
Takeshita, Kei ; Saisho, Yoshifumi ; Kitamura, Kumi ; Kaburagi, Noriko ; Funabiki, Tomohiro ; Inamura, Toshiyuki ; Oyamada, Yoshitaka ; Asano, Koichiro ; Yamaguchi, Kazuhiro. / Pneumonitis induced by ou-gon (scullcap). In: Internal Medicine. 2001 ; Vol. 40, No. 8. pp. 764-768.
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